Engelbrecht V, Schlaug G, Hefter H, Kahn T, Mödder U
Institute of Diagnostic Radiology, Heinrich-Heine University of Düsseldorf, Germany.
J Comput Assist Tomogr. 1995 Jul-Aug;19(4):635-8. doi: 10.1097/00004728-199507000-00026.
Repeat examinations in a de novo patient with Wilson disease revealed an expansion of decreased signal intensities in the basal ganglia on T2-weighted imaging after initiation of copper trapping therapy. Since marked clinical improvement was associated with continued urinary copper excretion, iron depositioning in exchange for copper might explain these findings.
对一名新发威尔逊病患者进行的重复检查显示，在开始铜螯合治疗后，T2加权成像上基底神经节的信号强度降低区域有所扩大。由于显著的临床改善与持续的尿铜排泄相关，铁沉积取代铜可能解释了这些发现。
