Falsey A R, Cunningham C K, Barker W H, Kouides R W, Yuen J B, Menegus M, Weiner L B, Bonville C A, Betts R F
Department of Medicine, Rochester General Hospital, New York, USA.
J Infect Dis. 1995 Aug;172(2):389-94. doi: 10.1093/infdis/172.2.389.
Respiratory syncytial virus (RSV) infections in the institutionalized elderly have been described; however, there is little information on the impact of RSV infection on community-dwelling elderly. The purpose of this study was to determine the relative numbers of hospitalizations associated with RSV infection and compare the clinical manifestations with influenza A infection. Between November and April during 1989-1992, persons > or = 65 years old hospitalized with acute cardiopulmonary conditions or influenza-like illnesses were evaluated. Evaluation included viral culture, RSV antigen detection, and serologic analysis; 159 (10%) of 1580 had RSV infection and 221 (11%) of 2091 had influenza A. RSV and influenza A cases occurred simultaneously throughout the 3 years. Clinical manifestations were similar; however, patients with RSV infection were more likely to receive therapy for bronchospasm. Death rates were 10% and 6% for RSV infection and influenza A, respectively. RSV infection is the cause of serious disease in community-dwelling older persons.
已有文献报道了机构养老老年人中的呼吸道合胞病毒（RSV）感染情况；然而，关于RSV感染对社区居住老年人的影响，相关信息却很少。本研究的目的是确定与RSV感染相关的住院人数，并将其临床表现与甲型流感感染进行比较。在1989 - 1992年的11月至4月期间，对因急性心肺疾病或流感样疾病住院的65岁及以上老人进行了评估。评估内容包括病毒培养、RSV抗原检测和血清学分析；1580例中有159例（10%）感染了RSV，2091例中有221例（11%）感染了甲型流感。在这3年中，RSV和甲型流感病例同时出现。临床表现相似；然而，RSV感染患者更有可能接受支气管痉挛治疗。RSV感染和甲型流感的死亡率分别为10%和6%。RSV感染是社区居住老年人严重疾病的病因。
