Quiñones-Molina R, Alaminos A, Molina H, Muñoz J, López G, Alvarez L, Ortega I, Piedra J, Soler W, Torres A
Centro Internacional de Restauración Neurológica, C. Habana, Cuba.
Stereotact Funct Neurosurg. 1994;63(1-4):52-5. doi: 10.1159/000100291.
From March 1991 to September 1993, 26 patients (aged 4-78 years) with brain tumors (4 glioblastoma multiforme, 10 nonglioblastoma multiforme, 1 mixed oligoastrocytoma, 2 carniopharyngiomas, 2 meningiomas and 7 metastases) were treated with stereotactic techniques at the Centro Internacional de Restauración Neurológica, La Habana, Cuba. A total of 28 stereotactic surgical procedures were performed with no operative mortality; they included biopsies in all cases, 1 stereotactic microsurgical resection and 12 permanent implants of 192Ir, followed by external beam fractionated radiation therapy (40-60 Gy). The present paper shows that the combined use of a stereotactic approach, a comprehensive and reliable stereotactic dosimetric planning system, stereotactic brachytherapy with 192Ir and complementary percutaneous radiation treatment constitutes a promising strategy for brain tumor management.
1991年3月至1993年9月，古巴哈瓦那国际神经康复中心采用立体定向技术治疗了26例脑肿瘤患者（年龄4 - 78岁），其中多形性胶质母细胞瘤4例，非多形性胶质母细胞瘤10例，混合性少突星形细胞瘤1例，颅咽管瘤2例，脑膜瘤2例，转移瘤7例。共进行了28次立体定向外科手术，无手术死亡病例；所有病例均包括活检，1例立体定向显微手术切除，12例192铱永久性植入，随后进行外照射分割放疗（40 - 60 Gy）。本文表明，立体定向方法、全面可靠的立体定向剂量规划系统、192铱立体定向近距离放疗和辅助经皮放射治疗的联合应用是脑肿瘤治疗的一种有前景的策略。
