Kletscher B A, Segura J W
Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Urology. 1995 Aug;46(2):168-72. doi: 10.1016/s0090-4295(99)80188-5.
Endoureterotomy and balloon dilation are techniques that have shown promise as treatment modalities for benign ureteral stricture disease. In this animal investigation, the results of a new endoureterotomy balloon that simultaneously incises and dilates the ureteral stricture via a retrograde approach are discussed.
Using the female pig model, 9 subjects with benign ureteral strictures were treated: 7 with the endoureterotomy balloon and 2 with balloon dilation only.
Success based on radiologic parameters and Whitaker testing was obtained in 5 of the 7 animals treated by endoureterotomy. In both animals treated by balloon dilation only, recurrent ureteral stricture disease developed.
This preliminary investigation suggests that this new device may be an effective treatment for benign ureteral stricture disease and that the further study in clinical trials is warranted.
输尿管内切开术和球囊扩张术已显示出有望成为治疗良性输尿管狭窄疾病的方法。在这项动物研究中，讨论了一种新型输尿管内切开球囊的结果，该球囊通过逆行途径同时切开并扩张输尿管狭窄。
使用雌性猪模型，对9例良性输尿管狭窄患者进行治疗：7例使用输尿管内切开球囊，2例仅使用球囊扩张。
接受输尿管内切开术治疗的7只动物中有5只基于放射学参数和惠特克测试取得了成功。仅接受球囊扩张治疗的两只动物均出现了复发性输尿管狭窄疾病。
这项初步研究表明，这种新装置可能是治疗良性输尿管狭窄疾病的有效方法，值得在临床试验中进一步研究。
