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新生儿抗-M所致溶血病

Haemolytic disease of the newborn due to anti-M.

作者信息

Duguid J K, Bromilow I M, Entwistle G D, Wilkinson R

机构信息

Mersey and North Wales Regional Transfusion Service, Liverpool, UK.

出版信息

Vox Sang. 1995;68(3):195-6. doi: 10.1111/j.1423-0410.1995.tb03927.x.

DOI:10.1111/j.1423-0410.1995.tb03927.x
PMID:7625079
Abstract

A patient with haemolytic disease of the newborn (HDN) due to anti-M which required exchange transfusion is described. Anti-M antibodies are usually assumed to be naturally occurring and to consist of immunoglobulin M (IgM); many however have an immunoglobin G (IgG) component. In view of this and the described occurrence of HDN, recommendations are made regarding the management of a pregnancy in which anti-M antibodies are detected.

摘要

本文描述了一名因抗-M导致新生儿溶血病(HDN)而需要进行换血治疗的患者。抗-M抗体通常被认为是天然存在的,且由免疫球蛋白M(IgM)组成;然而,许多抗-M抗体含有免疫球蛋白G(IgG)成分。鉴于此以及所描述的HDN病例,针对检测到抗-M抗体的妊娠管理提出了建议。

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