Park-Matsumoto Y C, Ogawa K, Tazawa T, Ishiai S, Tei H, Yuasa T
Department of Neurology, Akiba Memorial Hospital, Negishi Urawashi Saitama-ken, Japan.
Acta Neurol Scand. 1995 Apr;91(4):297-301. doi: 10.1111/j.1600-0404.1995.tb07009.x.
We described a 44-year old right-handed man showing mutism, left hemiplegia and pseudobulbar palsy after CT and MRI documented bilateral thalamo-capsular lesions by neuro-Behçet disease. Single photon emission tomography (SPECT) and Xenon CT revealed hypoperfusion of the bilateral frontal lobes. The pathophysiological mechanism of mutism was discussed and we postulate that mutism might occur as the result of frontal lobe dysfunction due to the disconnection of thalamocortical fiber from thalamus to frontal cortex and that it could be interpreted as an incomplete form of akinetic mutism.
我们描述了一名44岁的右利手男性，在CT和MRI证实其因神经白塞病出现双侧丘脑-豆状核病变后，表现为缄默症、左侧偏瘫和假性延髓麻痹。单光子发射断层扫描（SPECT）和氙CT显示双侧额叶灌注不足。我们讨论了缄默症的病理生理机制，并推测缄默症可能是由于丘脑皮质纤维从丘脑到额叶皮质的连接中断导致额叶功能障碍所致，并且可以将其解释为运动不能性缄默症的不完全形式。
