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Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer.

作者信息

Nicholson R I, Gee J M, Manning D L, Wakeling A E, Montano M M, Katzenellenbogen B S

机构信息

Tenovus Cancer Research Centre, University of Wales College of Medicine, Heath Park, United Kingdom.

出版信息

Ann N Y Acad Sci. 1995 Jun 12;761:148-63. doi: 10.1111/j.1749-6632.1995.tb31376.x.

DOI:10.1111/j.1749-6632.1995.tb31376.x
PMID:7625718
Abstract
摘要

相似文献

1
Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer.雌激素敏感性和抗性实验性及临床乳腺癌对纯抗雌激素药物(ICI 164384、ICI 182780)的反应。
Ann N Y Acad Sci. 1995 Jun 12;761:148-63. doi: 10.1111/j.1749-6632.1995.tb31376.x.
2
Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatment.对纯抗雌激素耐药的人乳腺癌细胞系对他莫昔芬治疗敏感。
Int J Cancer. 1995 May 16;61(4):529-34. doi: 10.1002/ijc.2910610417.
3
Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-1.雌激素调节基因在他莫昔芬耐药以及对ICI 164,384和ICI 182,780敏感的人乳腺癌细胞系MCF-7/TAMR-1中的表达改变。
Cancer Res. 1994 Mar 15;54(6):1587-95.
4
Anti-proliferative and anti-estrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast-cancer cells.ICI 164,384和ICI 182,780对4-羟基他莫昔芬耐药的人乳腺癌细胞的抗增殖和抗雌激素作用
Int J Cancer. 1994 Jan 15;56(2):295-300. doi: 10.1002/ijc.2910560225.
5
Pure antiestrogens and breast cancer.纯抗雌激素与乳腺癌
Curr Med Res Opin. 2001;17(4):282-9.
6
Action of "pure" antiestrogens in inhibiting estrogen receptor action.“纯”抗雌激素在抑制雌激素受体作用中的作用。
Breast Cancer Res Treat. 1993;26(2):131-7. doi: 10.1007/BF00689686.
7
Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer.在人乳腺癌模型中,纯甾体类抗雌激素与他莫昔芬的效果比较。
J Natl Cancer Inst. 1995 May 17;87(10):746-50. doi: 10.1093/jnci/87.10.746.
8
Effect of estrogen and antiestrogens on cell proliferation and synthesis of secreted proteins in the human breast cancer cell line MCF-7 and a tamoxifen resistant variant subline, AL-1.雌激素和抗雌激素对人乳腺癌细胞系MCF - 7及他莫昔芬耐药变异亚系AL - 1中细胞增殖和分泌蛋白合成的影响。
Acta Oncol. 1992;31(2):131-8. doi: 10.3109/02841869209088892.
9
Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens.人雌激素受体配体活性反转突变体:将抗雌激素解读为雌激素、将雌激素解读为抗雌激素并区分不同抗雌激素的受体。
Mol Endocrinol. 1996 Mar;10(3):230-42. doi: 10.1210/mend.10.3.8833652.
10
MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen.MCF7/LCC9:一种抗雌激素的MCF-7变体,其中对甾体抗雌激素ICI 182,780获得性耐药赋予了对非甾体抗雌激素他莫昔芬的早期交叉耐药性。
Cancer Res. 1997 Aug 15;57(16):3486-93.

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Bibliometric Analysis of The Global Research Trends on The Application of Tamoxifen in The Treatment of Breast Cancer Over The Past 50 Years.过去50年他莫昔芬在乳腺癌治疗中应用的全球研究趋势的文献计量分析
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Interaction between Estrogen Receptors and p53: A Broader Role for Tamoxifen?
雌激素受体与p53之间的相互作用:他莫昔芬的作用更广泛?
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Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells.靶向独特的配体结合域结构特征可下调Y537S ESR1突变乳腺癌细胞中的DKK1。
Breast Cancer Res. 2025 Jan 17;27(1):10. doi: 10.1186/s13058-024-01945-z.
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Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S Mutant Breast Cancer Cells.靶向独特的配体结合域结构特征可下调Y537S突变乳腺癌细胞中的DKK1。
Res Sq. 2024 Jun 25:rs.3.rs-4542467. doi: 10.21203/rs.3.rs-4542467/v1.
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Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S Mutant Breast Cancer Cells.靶向独特的配体结合域结构特征可下调Y537S突变乳腺癌细胞中的DKK1
bioRxiv. 2024 Jun 2:2024.05.28.596307. doi: 10.1101/2024.05.28.596307.
7
Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic response.转移性乳腺癌治疗中的挑战和机遇:优先递送至转移性细胞的纳米药物组合可能会增强治疗反应。
Pharmacol Ther. 2022 Aug;236:108108. doi: 10.1016/j.pharmthera.2022.108108. Epub 2022 Jan 6.
8
Suppression of breast cancer cells resistant to a pure anti-estrogen with CAR-transduced natural killer cells.用CAR转导的自然杀伤细胞抑制对纯抗雌激素耐药的乳腺癌细胞。
Am J Cancer Res. 2021 Sep 15;11(9):4455-4469. eCollection 2021.
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Computer-Aided Ligand Discovery for Estrogen Receptor Alpha.计算机辅助配体发现雌激素受体 α。
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Neuroprotective and neurotoxic outcomes of androgens and estrogens in an oxidative stress environment.雄激素和雌激素在氧化应激环境中的神经保护和神经毒性作用。
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