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在有节奏的外力作用与帕金森病静止性震颤之间产生的拍频。

Beats produced between a rhythmic applied force and the resting tremor of Parkinsonism.

作者信息

Walsh E G

出版信息

J Neurol Neurosurg Psychiatry. 1979 Jan;42(1):89-94. doi: 10.1136/jnnp.42.1.89.

DOI:10.1136/jnnp.42.1.89
PMID:762588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC490165/
Abstract

Rhythmic forces have been applied to the wrist of patients with Parkinsonism tremor by means of a printed motor. The tremor rate was not altered to that of the applied force. On the contrary, beats were established, the rate of which depended on the difference in rate between the tremor and the applied rhythm. Most of the observations have been for horizontal motion of the hand but similar phenomena have been seen for vertical movements, and for other parts of the body--for example, foot, elbow, finger joint, and head. The observations are regarded as supporting the view that the tremorgenic mechanism is central. There was no electromyographic evidence of servo driving or servo assistance in the genesis of the tremor.

摘要

已通过印刷电机向患有帕金森震颤的患者手腕施加有节奏的力。震颤频率并未改变为所施加力的频率。相反,出现了节拍,其频率取决于震颤频率与所施加节奏频率之间的差异。大多数观察是针对手部的水平运动,但垂直运动以及身体的其他部位——例如脚、肘部、手指关节和头部——也观察到了类似现象。这些观察结果被认为支持震颤发生机制是中枢性的观点。在震颤发生过程中,没有肌电图证据表明存在伺服驱动或伺服辅助。

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引用本文的文献

1
Characteristics of Rest and Postural Tremors in Parkinson's Disease: An Analysis of Motor Unit Firing Synchrony and Patterns.帕金森病静止性和姿势性震颤的特征:运动单位放电同步性及模式分析
Front Hum Neurosci. 2018 May 1;12:179. doi: 10.3389/fnhum.2018.00179. eCollection 2018.
2
Differential effects of changes in mechanical limb properties on physiological and pathological tremor.肢体力学特性变化对生理性和病理性震颤的不同影响。
J Neurol Neurosurg Psychiatry. 1987 May;50(5):568-79. doi: 10.1136/jnnp.50.5.568.

本文引用的文献

1
PROPRIOCEPTIVE ORIGIN OF PARKINSONIAN TREMOR.
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[Reflex factors in parkinsonian tremor].[帕金森震颤中的反射因素]
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The response of the tremor of patients with Parkinsonism to peripheral nerve stimulation.帕金森病患者震颤对外周神经刺激的反应。
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J Neurol Neurosurg Psychiatry. 1974 May;37(5):559-65. doi: 10.1136/jnnp.37.5.559.
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Clonus: beats provoked by the application of a rhythmic force.
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A mechanical-reflex oscillator hypothesis for parkinsonian hand tremor.帕金森病手部震颤的机械反射振荡器假说。
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10
Muscle spindle activity in alternating tremor of Parkinsonism and in clonus.
J Neurol Neurosurg Psychiatry. 1975 Jul;38(7):636-41. doi: 10.1136/jnnp.38.7.636.