Harris S S, Wood M J, Dawson-Hughes B
Calcium and Bone Metabolism Laboratory, USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA.
Bone. 1995 Apr;16(4 Suppl):311S-315S. doi: 10.1016/8756-3282(95)00050-n.
This study was conducted to report and compare bone mineral density (BMD) of the total body and distal forearm, as measured by X-ray absorptiometry, in 65 black and 73 white premenopausal women between the ages of 20 and 40. The black women had higher current and recalled body weights, a higher percent body fat, and more pregnancies and births, were younger at menarche, and reported lower alcohol intakes than the white women studied. A smaller percent of the black women had experienced amenorrhea, and a higher percent had lived at southern latitudes. Smoking history and lifetime use of oral contraceptives were similar in the two groups. Total body BMD, adjusted for body mass index (BMI), was 5.9% higher in the black than in the white women [mean +/- standard deviation (SD): 1.230 +/- 0.076 g/cm2 compared with 1.161 +/- 0.075; difference (95% confidence interval [CI95]: 0.068 (0.042, 0.095)]. Forearm BMD, adjusted for BMI, was 9.3% higher in the black women [mean +/- SD: 0.505 +/- 0.046 compared with 0.462 +/- 0.045; difference (CI95): 0.043 (0.027, 0.059)]. Adjustment for the other medical and lifestyle differences noted before had little effect on estimated BMD differences between the two groups.
本研究旨在报告并比较65名年龄在20至40岁之间的黑人绝经前女性和73名白人绝经前女性通过X线吸收法测量的全身和前臂远端骨矿物质密度(BMD)。与所研究的白人女性相比,黑人女性当前和回忆起的体重更高、体脂百分比更高、怀孕和生育次数更多、初潮年龄更小且报告的酒精摄入量更低。经历过闭经的黑人女性比例更小,而居住在南半球纬度地区的比例更高。两组的吸烟史和口服避孕药的终生使用情况相似。调整体重指数(BMI)后,黑人女性的全身BMD比白人女性高5.9%[平均值±标准差(SD):1.230±0.076g/cm²,相比之下为1.161±0.075;差异(95%置信区间[CI95]):0.068(0.042,0.095)]。调整BMI后,黑人女性的前臂BMD比白人女性高9.3%[平均值±SD:0.505±0.046,相比之下为0.462±0.045;差异(CI95):0.043(0.027,0.059)]。对之前提到的其他医学和生活方式差异进行调整后,对两组之间估计的BMD差异影响不大。