Santini F, Musazzi A, Bertolini P, Pugliese P, Fabbri A, Faggian G, Prioli A, Mazzucco A
Department of Cardiovascular Surgery, University of Verona Medical School, Italy.
J Card Surg. 1995 May;10(3):205-9. doi: 10.1111/j.1540-8191.1995.tb00600.x.
Between January 1992 and June 1994, 23 patients underwent surgery for aortic valve endocarditis at the Department of Cardiovascular Surgery of the University of Verona; a subgroup of 10 patients underwent aortic valve replacement with a porcine stentless valve (Biocor LTDA n = 8; Toronto SPV n = 2). There were 7 males and 3 females with a mean age of 56.3 years (range, 36 to 73 years). Eight patients had active endocarditis and two had healed endocarditis. Nine patients had native valve in endocarditis, the presence of a bicuspid aortic valve in 2, and 1 patient had recurrent prosthetic valve endocarditis (PVE), 7 of whom were in New York Heart Association (NYHA) Functional Class IV. The main indications for operation were congestive cardiac failure, active sepsis, and presence of large and mobile vegetations by echo and arrhythmias. There were no operative or late mortalities in this subgroup of patients. Short-term survival is 100% at a mean follow-up time of 11.2 months (range, 4 to 18 months), with no recurrent endocarditis or valve-related complications.
1992年1月至1994年6月期间，23例患者在维罗纳大学心血管外科接受了主动脉瓣心内膜炎手术；其中10例患者接受了猪无支架瓣膜主动脉瓣置换术（Biocor LTDA公司产品8例；多伦多SPV公司产品2例）。患者中有7名男性和3名女性，平均年龄56.3岁（范围为36至73岁）。8例患者患有活动性心内膜炎，2例患者的心内膜炎已愈合。9例患者为原发性瓣膜心内膜炎，其中2例存在二叶式主动脉瓣，1例患者为人工瓣膜心内膜炎（PVE）复发，其中7例属于纽约心脏协会（NYHA）心功能IV级。手术的主要指征为充血性心力衰竭、活动性脓毒症以及超声心动图显示存在大的活动赘生物和心律失常。该亚组患者无手术死亡或晚期死亡病例。平均随访时间为11.2个月（范围为4至18个月）时短期生存率为100%，无复发性心内膜炎或瓣膜相关并发症。
