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使用25%的戊二醛溶液来强化瓣环主动脉扩张、升主动脉和主动脉弓动脉瘤患者的主动脉。

The use of 25% glutaraldehyde solution to strengthen the aorta of patients with annuloaortic ectasia, ascending and aortic arch aneurysms.

作者信息

Rinaldi R G, Carballido J, Mojica J, Almodovar E A

机构信息

Cardiovascular Institute, Pavia Hospital, San Juan, Puerto Rico.

出版信息

J Card Surg. 1995 May;10(3):262-3. doi: 10.1111/j.1540-8191.1995.tb00607.x.

Abstract

Aortic friability is a problem of great concern and frustration for those performing operations on patients with ascending and arch aortic aneurysms, and particularly, on patients with annuloaortic ectasia. We have used 25% glutaraldehyde to successfully strengthen the distal aorta of three such patients. After the application, the aorta wall held sutures without tearing. Postoperative bleeding was minimal in each case. No neurological events were noticed, and all of the patients were discharged home within 2 weeks. The application of this tanning solution to such a friable aortic tissue should be considered as a helpful alternative to reduce postoperative bleeding, which is the most common complication after this type of surgery.

摘要

主动脉脆弱性是一个令那些为升主动脉和主动脉弓动脉瘤患者,尤其是为主动脉瓣环扩张患者进行手术的人极为关注和沮丧的问题。我们使用25%的戊二醛成功加固了三名此类患者的远端主动脉。应用后,主动脉壁能夹住缝线而不撕裂。每例术后出血均极少。未发现神经方面的情况,所有患者均在两周内出院。将这种鞣制溶液应用于如此脆弱的主动脉组织应被视为减少术后出血的一种有用的替代方法,术后出血是这类手术最常见的并发症。

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