Wengrovitz M, Healy D A, Diamond J R, Atnip R G
Department of Surgery, Pennsylvania State University College of Medicine, Hershey, USA.
J Cardiovasc Surg (Torino). 1995 Jun;36(3):241-6.
Five patients requiring dialysis for acute pulmonary edema and uremia from severe renal artery occlusive disease underwent surgical revascularization. Three patients with oliguria had excellent outcomes and remain dialysis-independent as long as twenty-four months following operation (mean serum creatinine 2.0 mg/dl). The two patients who were anuric both had technically successful operations but remained dialysis-dependent. Diagnostic evaluation of the azotemic patient suspected to have renal arterial occlusive disease should include a history and physical examination, urinalysis, renal ultrasound, and duplex scan of the renal arteries. In appropriate patients, arteriography should then be considered if other diagnoses appear unlikely. This algorithm may help identify those patients who might benefit from renal revascularization. It appears that oliguria rather than anuria and the angiographic demonstration of a patent distal vessel and nephrogram suggest a better functional outcome after revascularization. Unfortunately, the response to surgery cannot be reliably predicted and patient selection remains a challenge, but retrieval of renal function can be achieved in some cases even if patients are already being hemodialyzed.
五名因严重肾动脉闭塞性疾病导致急性肺水肿和尿毒症而需要透析的患者接受了手术血运重建。三名少尿患者术后效果极佳,术后长达24个月仍无需透析(平均血清肌酐2.0mg/dl)。两名无尿患者手术技术上均成功,但仍依赖透析。对疑似患有肾动脉闭塞性疾病的氮质血症患者进行诊断评估时,应包括病史和体格检查、尿液分析、肾脏超声以及肾动脉双功扫描。对于合适的患者,如果其他诊断不太可能,则应考虑进行动脉造影。该算法可能有助于识别那些可能从肾血运重建中获益的患者。似乎少尿而非无尿以及造影显示远端血管通畅和肾造影提示血运重建后功能结局更好。不幸的是,手术反应无法可靠预测,患者选择仍然是一项挑战,但即使患者已经在进行血液透析,在某些情况下仍可恢复肾功能。