环磷酸腺苷级联反应对增殖的正向调控：高功能腺瘤的一种致癌机制。 - Suppr

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超能文献

Positive control of proliferation by the cyclic AMP cascade: an oncogenic mechanism of hyper-functional adenoma.

作者信息

Ledent C, Parma J, Pirson I, Taton M, Roger P, Maenhaut C, Van Saude J, Pohl V, Lamy F, Parmentier M

机构信息

Institute of Interdisciplinary Research, University of Brussels, Belgium.

出版信息

J Endocrinol Invest. 1995 Feb;18(2):120-2. doi: 10.1007/BF03349717.

DOI:10.1007/BF03349717

PMID:7629377

Abstract

摘要

相似文献

Positive control of proliferation by the cyclic AMP cascade: an oncogenic mechanism of hyper-functional adenoma.环磷酸腺苷级联反应对增殖的正向调控：高功能腺瘤的一种致癌机制。

J Endocrinol Invest. 1995 Feb;18(2):120-2. doi: 10.1007/BF03349717.

Mutations of thyrotropin receptor isolated from thyroid autonomous functioning adenomas confer TSH-independent growth to thyroid cells.从甲状腺自主功能性腺瘤中分离出的促甲状腺激素受体突变赋予甲状腺细胞不依赖促甲状腺激素的生长特性。

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Primary culture of cells from hyperfunctioning thyroid adenoma with an activating mutation of G alphas.伴有Gα激活突变的高功能甲状腺腺瘤细胞的原代培养

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Activation of the cAMP cascade in thyroid autonomy.

Exp Clin Endocrinol Diabetes. 1998;106 Suppl 4:S4-5. doi: 10.1055/s-0029-1212047.

Activation of the cyclic AMP cascade as an oncogenic mechanism: the thyroid example.环磷酸腺苷级联反应的激活作为一种致癌机制：以甲状腺为例。

Biochimie. 1991 Jan;73(1):29-36. doi: 10.1016/0300-9084(91)90070-h.

The TSH cyclic AMP cascade in the control of thyroid cell proliferation: the story of a concept.促甲状腺激素环磷酸腺苷级联反应对甲状腺细胞增殖的调控：一个概念的历程

Thyroidology. 1991 Dec;3(3):97-101.

[From diffuse goiter to nodular goiter].[从弥漫性甲状腺肿到结节性甲状腺肿]

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Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma.毒性多结节性甲状腺肿中的高功能甲状腺结节与孤立性毒性腺瘤一样，都存在激活促甲状腺激素受体突变。

J Clin Endocrinol Metab. 1998 Feb;83(2):492-8. doi: 10.1210/jcem.83.2.4559.

Induction of specific phosphodiesterase isoforms by constitutive activation of the cAMP pathway in autonomous thyroid adenomas.自主性甲状腺腺瘤中cAMP途径的组成性激活对特定磷酸二酯酶同工型的诱导作用。

J Clin Endocrinol Metab. 2000 Aug;85(8):2872-8. doi: 10.1210/jcem.85.8.6712.

[Transgenic mouse models. Their interest in thyroid tumors].

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本文引用的文献

Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.促甲状腺激素受体基因的体细胞突变会导致甲状腺功能亢进性腺瘤。

Nature. 1993 Oct 14;365(6447):649-51. doi: 10.1038/365649a0.

Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.促甲状腺激素（TSH）受体第三细胞质环不同区域的替换对组成性、TSH和TSH受体自身抗体刺激的磷酸肌醇及3',5'-环磷酸腺苷信号生成具有选择性作用。

Mol Endocrinol. 1993 Aug;7(8):1009-20. doi: 10.1210/mend.7.8.7901757.

Pathogenesis of autonomous thyroid nodules: in vitro study of iodine and adenosine 3',5'-monophosphate metabolism.自主性甲状腺结节的发病机制：碘与3',5'-环磷酸腺苷代谢的体外研究

J Clin Endocrinol Metab. 1988 Mar;66(3):570-9. doi: 10.1210/jcem-66-3-570.

Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies.人促甲状腺激素（TSH）受体的克隆、测序及表达：自身抗体结合的证据

Biochem Biophys Res Commun. 1989 Dec 29;165(3):1250-5. doi: 10.1016/0006-291x(89)92736-8.

The cyclic AMP-mediated stimulation of cell proliferation.环磷酸腺苷介导的细胞增殖刺激。

Trends Biochem Sci. 1989 Feb;14(2):67-71. doi: 10.1016/0968-0004(89)90046-7.

Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice.转基因小鼠中甲状腺球蛋白-氯霉素乙酰转移酶融合基因的组织特异性表达与甲基化

Proc Natl Acad Sci U S A. 1990 Aug;87(16):6176-80. doi: 10.1073/pnas.87.16.6176.

Regulation of protooncogenes c-fos and c-myc expressions by protein tyrosine kinase, protein kinase C, and cyclic AMP mitogenic pathways in dog primary thyrocytes: a positive and negative control by cyclic AMP on c-myc expression.蛋白酪氨酸激酶、蛋白激酶C和环磷酸腺苷促有丝分裂途径对犬原代甲状腺细胞中原癌基因c-fos和c-myc表达的调控：环磷酸腺苷对c-myc表达的正负调控

Exp Cell Res. 1990 Jul;189(1):33-40. doi: 10.1016/0014-4827(90)90253-7.

RDC8 codes for an adenosine A2 receptor with physiological constitutive activity.

Biochem Biophys Res Commun. 1990 Dec 31;173(3):1169-78. doi: 10.1016/s0006-291x(05)80909-x.

Activation of the cyclic AMP cascade as an oncogenic mechanism: the thyroid example.环磷酸腺苷级联反应的激活作为一种致癌机制：以甲状腺为例。

Biochimie. 1991 Jan;73(1):29-36. doi: 10.1016/0300-9084(91)90070-h.

Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices.与促甲状腺激素不同，甲状腺刺激抗体不会激活人甲状腺切片中的磷脂酶C。

J Clin Invest. 1991 May;87(5):1634-42. doi: 10.1172/JCI115178.

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