Otto S E
J Intraven Nurs. 1995 Jul-Aug;18(4):170-6.
Multiple solid tumors are unresponsive to chemotherapy drug levels that are given by systemic administration. Regional chemotherapy administration provides a higher drug concentration at and/or near the tumor site, thus achieving a higher tumor cell kill. Intravenous therapy nurses are involved in the access of the multiple devices, infusion of the chemotherapy drugs, and monitoring of the patient for the duration of the regional therapy. This article will provide a review of regional chemotherapy via intraarterial, intrathecal, and intraperitoneal routes. Nursing management will focus on the specifics of drug delivery and the care of the patient receiving regional chemotherapy.
多种实体瘤对全身给药的化疗药物水平无反应。区域化疗给药可在肿瘤部位和/或其附近提供更高的药物浓度，从而实现更高的肿瘤细胞杀伤率。静脉治疗护士参与多种设备的接入、化疗药物的输注以及区域治疗期间患者的监测。本文将综述经动脉、鞘内和腹腔途径的区域化疗。护理管理将侧重于药物递送的具体细节以及接受区域化疗患者的护理。
