Suez D
J Intraven Nurs. 1995 Jul-Aug;18(4):178-90.
Although intravenous immunoglobulin therapy is used mainly as a replacement therapy in humoral immune deficiency disorders and congenital or acquired conditions, the indications for its use have expanded over the last decade to other disease states, such as autoimmune diseases and variable chronic inflammatory syndromes. The ability to administer large achieving rapidly effective serum immunoglobulin G levels under painless conditions are the main advantages of this form of therapy. Intravenous immunoglobulin therapy has a high safety record although side effects range from mild anaphylactoid reactions to potential life-threatening reactions. It is essential to understand the underlying mechanisms of these potential reactions to assure safe administration.
尽管静脉注射免疫球蛋白疗法主要用作体液免疫缺陷疾病以及先天性或后天性疾病的替代疗法，但在过去十年中，其应用指征已扩展到其他疾病状态，如自身免疫性疾病和各种慢性炎症综合征。在无痛条件下快速达到有效的血清免疫球蛋白G水平的给药能力是这种治疗方式的主要优点。静脉注射免疫球蛋白疗法有很高的安全记录，尽管副作用范围从轻度类过敏反应到潜在的危及生命的反应。了解这些潜在反应的潜在机制对于确保安全给药至关重要。
