Khoury J, Nasrallah T, Raad J
Service de Cardiologie, Hôpital Militaire, Beyrouth, Liban.
J Med Liban. 1993;41(4):236-9.
Pregnancy with mechanical mitral prosthesis poses several risks either for the fetus and the mother. A good care including the contribution of an obstetrician, a cardiologist, an anesthesiologist and a neonatologist is strongly recommended during pregnancy until delivery. The anticoagulation causes a major risk. The heparin may be given during the whole pregnancy or may be replaced by the oral anticoagulants from the 13 weeks of last menstrual period until 10 to 15 days before delivery. Considering the difficulty to have an adequate anticoagulation with subcutaneous heparin, we have tried in ambulatory with our patient the intravenous heparin under a strict observation.
机械二尖瓣置换术后妊娠对胎儿和母亲都有一些风险。强烈建议在孕期直至分娩期间进行良好的护理，包括产科医生、心脏病专家、麻醉师和新生儿科医生的共同参与。抗凝治疗存在重大风险。肝素可在整个孕期使用，也可自末次月经第13周起至分娩前10至15天用口服抗凝剂替代。考虑到皮下注射肝素难以实现充分抗凝，我们在门诊对患者尝试了在严格观察下静脉注射肝素。
