Patiutko Iu I, Ignatiuk V G, Lagoshnyĭ A T, Bogov R K, Dolgushin B I
Khirurgiia (Mosk). 1995(3):26-9.
The results of treatment of 86 patients who had been subjected to gastro-pancreatoduodenal resection in the period from 1975 to 1992 were studied. The patients were divided into two groups. The main cause of postoperative mortality in the first group was the development of pancreonecrosis and incompetence of the pancreatico-enteral anastomosis. Hypothermia of the pancreatic duct and introduction of 5-fluorouracil into the pancreatic duct reduced postoperative mortality among patients of the second group from 34.9% to 13.9%. It is shown that this method may be applied in wide surgical practice.
对1975年至1992年间接受胃胰十二指肠切除术的86例患者的治疗结果进行了研究。患者被分为两组。第一组术后死亡的主要原因是胰腺坏死和胰肠吻合口功能不全。胰管低温并向胰管内注入5-氟尿嘧啶使第二组患者的术后死亡率从34.9%降至13.9%。结果表明，该方法可广泛应用于外科手术实践。
