Wang C Y, Brodland D G, Su W P
Department of Dermatology, Mayo Clinic Rochester, Minnesota 55905, USA.
Mayo Clin Proc. 1995 Aug;70(8):766-72. doi: 10.4065/70.8.766.
To describe the types of skin cancer associated with the acquired immunodeficiency syndrome (AIDS).
A literature review of AIDS-related mucocutaneous neoplasms, including basal cell carcinoma, squamous cell carcinoma, bowenoid papulosis and Bowen's disease, squamous cell carcinoma, cloacogenic carcinoma, and malignant melanoma, is presented, and the incidence, etiopathogenesis, clinicopathologic features, treatment, and prognosis are discussed.
The association between cutaneous neoplasms and AIDS is well known. Neoplasms seem to grow more rapidly and be more invasive in patients with AIDS than in other groups of patients. Several oncogenic factors--for example, sunlight exposure or human papillomavirus infection--have been associated with the development of skin cancer in these patients. The morbidity and mortality rates of skin cancer are higher in patients infected with the human immunodeficiency virus (HIV) than in the general population. Early and complete excision of the neoplasm is especially important.
A link exists between AIDS and the development of skin cancer. HIV-infected patients should be followed up vigilantly for early diagnosis of skin cancer. Because these patients are less able to suppress common cutaneous malignant disease due to their immunocompromised status, biopsy specimens should be obtained from all suspicious lesions, and histopathologic assessment should be done.
描述与获得性免疫缺陷综合征（艾滋病）相关的皮肤癌类型。
对艾滋病相关的黏膜皮肤肿瘤进行文献综述，包括基底细胞癌、鳞状细胞癌、鲍温样丘疹病和鲍温病、鳞状细胞癌、泄殖腔源癌及恶性黑色素瘤，并讨论其发病率、病因发病机制、临床病理特征、治疗及预后。
皮肤肿瘤与艾滋病之间的关联已为人熟知。与其他患者群体相比，艾滋病患者的肿瘤似乎生长更快且侵袭性更强。一些致癌因素，如阳光照射或人乳头瘤病毒感染，与这些患者皮肤癌的发生有关。感染人类免疫缺陷病毒（HIV）的患者皮肤癌的发病率和死亡率高于普通人群。肿瘤的早期完整切除尤为重要。
艾滋病与皮肤癌的发生之间存在联系。应对HIV感染患者进行密切随访以便早期诊断皮肤癌。由于这些患者因免疫功能低下而较难抑制常见的皮肤恶性疾病，因此应从所有可疑病变处获取活检标本并进行组织病理学评估。
