Dogali M, Devinsky O, Luciano D, Perrine K
Department of Neurosurgery, NYU Medical Center-Hospital for Joint Diseases, New York, USA.
Stereotact Funct Neurosurg. 1994;62(1-4):222-5. doi: 10.1159/000098623.
Invasive intracranial monitoring with subdural grids has led to a greater appreciation of cortical function and the discovery of ictal onset either independently or in conjunction with deep structures. With the description of multiple subpial transections the armamentarium for surgical control of intractable seizures has been expanded. Utilizing invasive intracranial monitoring with subdural grids and strips, a large series of patients with intractable complex partial seizures originating in exquisite cortex, and in some cases additionally in deep structures, have undergone surgery. These patients would previously have been judged not to be candidates for surgical control of seizures. We will present 9-month or greater follow-up in an ongoing series of patients undergoing cortical resection and subpial transections in whom there has been a statistical improvement in control or alleviation of their seizure disorder. The report will specifically discuss outcomes as related to exquisite cortex, motor, sensory and language functions, as well as clinical results and EEG.
使用硬膜下电极格栅进行有创颅内监测，使人们对皮质功能有了更深入的认识，并发现了癫痫发作起始于皮质独立区域或与深部结构共同作用的情况。随着多软膜下横切术的描述，用于外科治疗难治性癫痫的手段得到了扩展。利用硬膜下电极格栅和条状电极进行有创颅内监测，一大批起源于精细皮质、部分病例还累及深部结构的难治性复杂部分性癫痫患者接受了手术治疗。这些患者以前会被判定不适合进行癫痫手术治疗。我们将展示一系列正在接受皮质切除术和软膜下横切术患者的9个月及更长时间的随访结果，这些患者在癫痫控制或缓解方面有统计学上的改善。该报告将具体讨论与精细皮质、运动、感觉和语言功能相关的结果，以及临床结果和脑电图情况。
