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按蚊体内的促进作用与丝虫病的自然消失:这一概念是否已得到充分证据的验证?

Facilitation in Anopheles and spontaneous disappearance of filariasis: has the concept been verified with sufficient evidence?

作者信息

Wada Y, Kimura E, Takagi M, Tsuda Y

机构信息

Department of Medical Entomology, Nagasaki University, Japan.

出版信息

Trop Med Parasitol. 1995 Mar;46(1):27-30.

PMID:7631124
Abstract

The validity of recently much argued phenomenon of facilitation in the transmission of filariasis was considered by examining previously published papers. It was concluded that there was no clear evidence to support the existence of facilitation and facilitation-based unstable equilibrium in relation to microfilaria prevalence and density in human population below which filariasis would spontaneously disappear, even when the vector was Anopheles mosquitoes. Instead, the existence of a critical level of man/mosquito contacts for the disappearance of filariasis was suggested.

摘要

通过查阅此前发表的论文,对近期备受争议的丝虫病传播促进现象的有效性进行了考量。得出的结论是,没有明确证据支持促进作用以及基于促进作用的不稳定平衡的存在,这种平衡与人群中微丝蚴流行率和密度相关,低于该水平丝虫病就会自发消失,即便传播媒介是按蚊。相反,有人提出存在一个丝虫病消失所需的人与蚊子接触的临界水平。

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