Steckler T L
Department of Internal Medicine, University of Nevada School of Medicine, Las Vegas 89102, USA.
South Med J. 1995 Aug;88(8):858-9. doi: 10.1097/00007611-199508000-00015.
Central pontine myelinolysis is classically described in alcoholics or other malnourished individuals after correction of severe hyponatremia. A patient with bulimia developed central pontine myelinolysis after correction of severe hyponatremia and hypokalemia. Early symptoms of abnormal affect and dystonia made initial diagnosis elusive. The spectrum of neurologic signs and possible causes of central pontine myelinolysis are discussed. A conservative approach to treatment of hyponatremia is advocated.
经典型的脑桥中央髓鞘溶解症常见于酗酒者或其他营养不良的个体在严重低钠血症得到纠正之后。一名贪食症患者在严重低钠血症和低钾血症得到纠正后发生了脑桥中央髓鞘溶解症。情感异常和肌张力障碍的早期症状使得最初的诊断难以捉摸。本文讨论了脑桥中央髓鞘溶解症的神经系统体征范围及可能病因。提倡采用保守方法治疗低钠血症。