Andreassen B U, Andersen K, Ebbesen F
Børneafdelingen, Aalborg Sygehus.
Ugeskr Laeger. 1995 Jun 5;157(23):3326-30.
We reviewed the clinical presentation, subsequent course and outcome of 45 newborn infants with neuotizing enterocolitis (NEC) seen on eight neonatal intensive care units during a 10 year period (01.01.82-31.12.91). The average incidence of NEC was found to be 1.2 (0.3-3.8) per 10,000 liveborn infants with a tendency to increase during the period. Eighteen percent had a birth weight of less than 1,000 g. Thirty-six percent had a birthweight between 1,000 and 1,500 g. Twenty-nine percent had a birthweight between 1,500 and 2,500 g. The last group made up of 16% had birth weights above 2,500 g. The mortality was determined by the severity of the disease, being 0% for infants within Bell's stage I, 25% in Bell's stage II and 71% in Bell's stage III. Sixty-nine percent of the infants were diagnosed in stage III, probably because of low attention to NEC in its early stages. The prognosis of surviving infants was good with no gastrointestinal symptoms when evaluated four to five years later.