Tsitsopoulos P D, Tsonidis C A, Tsoleka K D, Tavridis G N
University Department of Neurosurgery, Aristotle University of Thessaloniki, Ippokration General Hospital, Greece.
Br J Neurosurg. 1995 Apr;9(2):227-32. doi: 10.1080/02688699550041610.
In order to study the contribution of the radicular arteries to the blood supply of the spinal cord, we performed experimental occlusion of these arteries in cats. In 43 cats, under thiopental anaesthesia, unilateral, bilateral, single or multiple ligations of dorsal radicular arteries were carried out. The animals were killed at the 1st, 2nd and 7th postoperative day. The spinal cords were removed and preserved in formalin solution for 1 month and then examined, using light microscopy. We conclude that bilateral or multiple ligations are capable of producing ischaemic lesions in the spinal cord, more profound by the seventh postoperative day, while single ligations do not produce such lesions, unless a medullary artery is involved. The ischaemic lesions which were observed were associated with clinical neurological deficits.
为了研究根动脉对脊髓血液供应的贡献，我们对猫进行了这些动脉的实验性闭塞。在43只猫中，在硫喷妥钠麻醉下，对背根动脉进行单侧、双侧、单次或多次结扎。在术后第1天、第2天和第7天处死动物。取出脊髓并在福尔马林溶液中保存1个月，然后用光学显微镜检查。我们得出结论，双侧或多次结扎能够在脊髓中产生缺血性病变，术后第七天更为严重，而单次结扎除非累及髓动脉，否则不会产生此类病变。观察到的缺血性病变与临床神经功能缺损有关。
