Barrett A W, Bennett J H, Speight P M
Joint Department of Oral Pathology, Eastman Dental Institute, London, UK.
Eur J Cancer B Oral Oncol. 1995 Mar;31B(2):100-5. doi: 10.1016/0964-1955(94)00036-4.
Nine cases of primary oral mucosal melanoma in Caucasian patients were reviewed and the tumours analysed for expression of S100, HMB45, NKI/C3, HLA-DR, PCNA, cytokeratin and von Willebrand factor. The clinical, histopathological and immunohistochemical features were quite distinctive and our findings support previous suggestions that oral melanoma should be classified as a separate entity rather than as a sub-type of cutaneous melanoma.
对9例白种人原发性口腔黏膜黑色素瘤患者进行了回顾性研究，并分析了肿瘤中S100、HMB45、NKI/C3、HLA-DR、PCNA、细胞角蛋白和血管性血友病因子的表达情况。其临床、组织病理学和免疫组化特征颇为独特，我们的研究结果支持先前的观点，即口腔黑色素瘤应归类为一个独立的实体，而非皮肤黑色素瘤的一个亚型。
