Kanamori N, Sakai K, Sei H, Bouvard A, Salvert D, Vanni-Mercier G, Jouvet M
Départment de Médecine Expérimentale, Université Claude Bernard, Lyon, France.
Brain Res Bull. 1995;37(5):545-9. doi: 10.1016/0361-9230(95)00030-i.
We investigated the effects of decerebration on long-term variations in arterial blood pressure during paradoxical sleep (PS) in cats. In normal cats, the blood pressure decreased during the transition from slow wave sleep to PS and maintained its lower level throughout PS for several days after surgery. After this early postoperative stage, however, the arterial hypotension was replaced by tonic and phasic rises in blood pressure during PS. Such long-term changes in blood pressure were completely abolished when the brain stem was transected at the ponto-mesencephalic junction, and the cats consistently exhibited a sustained fall in blood pressure throughout the survival periods of 1 month or more.
我们研究了去大脑对猫异相睡眠（PS）期间动脉血压长期变化的影响。在正常猫中，血压在从慢波睡眠过渡到PS时下降，并在术后数天的整个PS期间维持在较低水平。然而，在术后早期阶段之后，PS期间的动脉低血压被血压的紧张性和阶段性升高所取代。当在脑桥-中脑交界处横断脑干时，这种血压的长期变化完全消失，并且猫在1个月或更长时间的存活期内始终表现出血压持续下降。
