Kanamori N, Sakai K, Sei H, Salvert D, Vanni-Mercier G, Yamamoto M, Jouvet M
Département de Médecine Expérimentale, Université Claude Bernard, Lyon, France.
Arch Ital Biol. 1994 Mar;132(2):105-15.
Arterial blood pressure fluctuations during sleep were investigated with power analysis technique in both normal and decerebrate cats. In the initial postoperative stage lasting about 3 to 4 days, intact cats displayed, during paradoxical sleep, phasic increases in arterial blood pressure which were superimposed on a tonic hypotension. In the later chronic stage, however, the animals showed the phasic hypertension being superimposed on the background of a tonic hypertension. Regardless of these stages, the blood pressure during paradoxical sleep exhibited a 1/f-like spectrum, expressed by the power spectral density which is inversely proportional to the Fourier frequency f. On the other hand, a power spectral profile of the blood pressure during slow wave sleep presented a white noise-like pattern within the same frequency range of 0.1-0.01 Hz. After brainstem transections at the pontomesencephalic border, the cats exhibited consistently a sustained fall in blood pressure during paradoxical sleep and the power spectral density of the blood pressure displayed a white noise-like pattern throughout the survival periods of one month or more. These observations indicate that the blood pressure fluctuations in the 1/f spectrum during paradoxical sleep originate in rostral brain structures.
利用功率分析技术，对正常猫和去大脑猫睡眠期间的动脉血压波动情况进行了研究。在术后最初持续约3至4天的阶段，完整的猫在异相睡眠期间，动脉血压呈现出阶段性升高，并叠加在持续性低血压之上。然而，在后期的慢性阶段，动物表现出阶段性高血压叠加在持续性高血压的背景之上。无论处于哪个阶段，异相睡眠期间的血压呈现出1/f样频谱，由功率谱密度表示，其与傅里叶频率f成反比。另一方面，慢波睡眠期间血压的功率谱分布在0.1 - 0.01Hz的相同频率范围内呈现出类似白噪声的模式。在脑桥中脑边界处进行脑干横切后，猫在异相睡眠期间血压持续下降，并且在长达一个月或更长时间的存活期内，血压的功率谱密度呈现出类似白噪声的模式。这些观察结果表明，异相睡眠期间1/f频谱中的血压波动起源于脑桥以上的脑结构。
