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脉冲直流电刺激下牵张骨痂的骨密度变化

Bone mineral density changes in distracted callus stimulated by pulsed direct electrical current.

作者信息

Hamanishi C, Kawabata T, Yoshii T, Tanaka S

机构信息

Department of Orthopaedic Surgery, Kinki University School of Medicine, Osaka, Japan.

出版信息

Clin Orthop Relat Res. 1995 Mar(312):247-52.

PMID:7634610
Abstract

To evaluate the effect of application of pulsed direct current electrical stimulation to callus tissue, a 1-cm bone-lengthening model using an external lengthener was applied to rabbit tibia. Twenty-microampere pulsed direct current was applied 12 hours daily from the day of osteotomy until 40 days after the completion of lengthening. The area, bone mineral content, and bone mineral density of the distracted callus and of the proximal and distal segments of the tibia were evaluated using dual-energy xray absorptiometry. The absolute and relative values of bone mineral density of the electrically stimulated callus were significantly increased as compared with those in the control group. Pulsed direct current electrical stimulation may be indicated in bone lengthening to stimulate the poorly mineralized callus, and may shorten the overall time course of leg lengthening.

摘要

为评估脉冲直流电刺激对骨痂组织的作用,采用外置延长器建立兔胫骨1厘米骨延长模型。自截骨日起至延长完成后40天,每天施加20微安脉冲直流电12小时。使用双能X线吸收法评估牵张骨痂以及胫骨近端和远端节段的面积、骨矿物质含量和骨矿物质密度。与对照组相比,电刺激骨痂的骨矿物质密度绝对值和相对值均显著增加。脉冲直流电刺激可能适用于骨延长,以刺激矿化不良的骨痂,并可能缩短腿部延长的总时间进程。

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