Mühlbauer W, Henckel von Donnersmarck G, Hoefter E, Hartinger A
Abteilung für Plastische-, Wiederherstellende- und Handchirurgie, Städtisches Krankenhaus München Bogenhausen.
Chirurg. 1995 Apr;66(4):271-6.
The culture and transplantation of keratinocytes are considered an important progress in the treatment of severe burns. The keratinocyte grafts take best (50 to 90%) on remaining dermal structures after deep dermal (II b) burns. Since 1988 we culture also donor keratinocytes. They are cryopreserved in the 'skin bank' in large quantities. As vital wound cover they allow for a rapid and near scarless reepithelialization. For deep (III) burns we use composite grafts of cultured auto-keratinocytes on allo-dermis with increasing success (up to 75% take rate) without rejection.
角质形成细胞的培养和移植被认为是重度烧伤治疗中的一项重要进展。角质形成细胞移植物在深二度（II b）烧伤后残留的真皮结构上成活率最高（50%至90%）。自1988年以来，我们也培养供体角质形成细胞。它们被大量冷冻保存在“皮肤库”中。作为重要的伤口覆盖物，它们能实现快速且近乎无痕的再上皮化。对于三度烧伤，我们使用培养的自体角质形成细胞与同种异体真皮的复合移植物，成功率不断提高（成活率高达75%）且无排斥反应。
