Imhof M, Ohmann C, Röher H D
Klinik für Allgemein- und Unfallchirurgie, Heinrich-Heine-Universität Düsseldorf.
Chirurg. 1995 Apr;66(4):360-5.
Acute acalculous cholecystitis (AAC) is a well-known complication in postoperative and severely traumatized patients. Existing data of AAC originate from retrospective analyses and episodic case reports. In a prospective study 45 polytraumatized patients admitted to our intensive care unit between January 1, 1989 and June 30, 1990 were clinically and sonographically screened for this condition at defined time-intervals. A clinical and sonographical follow-up was performed annually (1991-1993). Trauma scoring was performed according to the Injury Severity Score (ISS) and Polytrauma Score (PTS). AAC was defined as a combination of hydrops of the gallbladder, an increased mural thickness (> 3.5 mm) and the demonstration of sludge. We were able to demonstrate this diagnostic triad in 8 out of 45 patients (18%). As a consequence early elective cholecystectomy was performed in one patient. The remaining patients were treated conservatively. Incidence of AAC in severely traumatized patients is probably higher than figures so far published suggest. The systematic search for this condition using serial sonographic examinations and defined sonomorphological criteria may select individual cases for elective cholecystectomy. Ultrasound is a reliable method of early detection and follow-up of this complication. Trauma and following intensive care therapy induce a lithogenetic factor, developing gallstone disease in 27% of patients within an 2-3-year interval.
急性非结石性胆囊炎(AAC)是术后患者和严重创伤患者中一种众所周知的并发症。AAC的现有数据来自回顾性分析和偶发病例报告。在一项前瞻性研究中,对1989年1月1日至1990年6月30日期间入住我们重症监护病房的45例多发伤患者,在规定的时间间隔进行了临床和超声检查以筛查这种疾病。每年(1991 - 1993年)进行临床和超声随访。根据损伤严重程度评分(ISS)和多发伤评分(PTS)进行创伤评分。AAC被定义为胆囊积液、胆囊壁厚度增加(> 3.5 mm)和出现胆泥的组合。我们在45例患者中的8例(18%)中证实了这一诊断三联征。因此,对1例患者进行了早期择期胆囊切除术。其余患者接受保守治疗。严重创伤患者中AAC的发生率可能高于迄今公布的数据所显示的数字。使用系列超声检查和明确的超声形态学标准对这种疾病进行系统筛查,可以选择个别病例进行择期胆囊切除术。超声是早期发现和随访这种并发症的可靠方法。创伤和随后的重症监护治疗会诱发致石因素,在2 - 3年的时间间隔内,27%的患者会发生胆结石疾病。