Koutouby A, Habibullah J
Department of Pediatrics, Al Wasl Maternity & Pediatric Hospital, Dubai, United Arab Emirates.
J Trop Pediatr. 1995 Jun;41(3):177-80. doi: 10.1093/tropej/41.3.177.
The case records of all neonates admitted to the neonatal unit of Al Wasl Hospital (Dubai) in a period of 60 months (May 1987-April 1992) were analysed. One-hundred-and-six neonates had confirmed sepsis. The most common causative organisms were Group B Streptococci (23 per cent), E. coli (17 per cent), Staph. epidermidis (17 per cent), and Klebsiella pneumoniae (16 per cent). Group B Streptococcus presented as the most common organism in very early (< or = 24 hours) and early onset (2-6 days) of sepsis (34 per cent, 21/61), Klebsiella pneumoniae (24 per cent), Staphylococcal epidermidis (18 per cent) and Candida (13 per cent) were most common organisms causing late onset of sepsis (7-30 days). Pseudomonas aeruginosa and Klebsiella pneumoniae had highest mortality (71 per cent, 5/7; and 59 per cent, 10/17, respectively). Lowest mortality (4 per cent, 1/25) was observed in Group B Streptococcus sepsis. Prematurity, low birth weight, and nosocomial sepsis were high risk factors associated with fatal outcome.
对1987年5月至1992年4月这60个月期间入住迪拜瓦斯尔医院新生儿病房的所有新生儿的病历进行了分析。106例新生儿确诊为败血症。最常见的致病菌是B族链球菌（23%）、大肠杆菌（17%）、表皮葡萄球菌（17%）和肺炎克雷伯菌（16%）。B族链球菌是败血症极早期（≤24小时）和早期（2 - 6天）最常见的致病菌（34%，21/61），肺炎克雷伯菌（24%）、表皮葡萄球菌（18%）和念珠菌（13%）是导致败血症晚期（7 - 30天）的最常见致病菌。铜绿假单胞菌和肺炎克雷伯菌的死亡率最高（分别为71%，5/7；和59%，10/17）。B族链球菌败血症的死亡率最低（4%，1/25）。早产、低出生体重和医院感染性败血症是与致命结局相关的高危因素。
