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腹腔镜检查在两性畸形患者中的应用。

Use of laparoscopy in intersex patients.

作者信息

Yu T J, Shu K, Kung F T, Eng H L, Chen H Y

机构信息

Department of Urology, Chang Gung Medical College, Kaohsiung, Taiwan.

出版信息

J Urol. 1995 Sep;154(3):1193-6.

PMID:7637087
Abstract

PURPOSE

Management of impalpable gonads in intersex patients remains a challenging problem. Since laparoscopic gonadectomy or gonadal preservation has been used in the management of impalpable gonads in the normal male population, laparoscopy can be an alternative method in the treatment of intersex patients.

MATERIALS AND METHODS

Laparoscopic operations were performed on 6 patients with intersex conditions, including the testicular feminization syndrome in 2, 17 beta-hydroxysteroid dehydrogenase deficiency in 1, 5 alpha-reductase deficiency in 1 and mixed gonadal dysgenesis in 2.

RESULTS

Laparoscopic gonadal biopsy, gonadectomy and hysterosalpingectomy were done in select patients.

CONCLUSIONS

Although the initial diagnoses were made by phenotypic presentation, and biochemical and cytogenetic studies, laparoscopy had an important role in defining the internal ductal and gonadal structures to confirm the diagnosis, and served as an efficient method for gonadectomy and removing structures contrary to the assigned gender.

摘要

目的

两性畸形患者中无法触及性腺的管理仍然是一个具有挑战性的问题。由于腹腔镜性腺切除术或性腺保留术已用于正常男性人群中无法触及性腺的管理,因此腹腔镜检查可作为治疗两性畸形患者的一种替代方法。

材料与方法

对6例两性畸形患者进行了腹腔镜手术,其中包括2例睾丸女性化综合征、1例17β-羟类固醇脱氢酶缺乏症、1例5α-还原酶缺乏症和2例混合性性腺发育不全。

结果

对部分患者进行了腹腔镜性腺活检、性腺切除术和子宫输卵管切除术。

结论

尽管最初的诊断是通过表型表现、生化和细胞遗传学研究做出的,但腹腔镜检查在确定内部导管和性腺结构以确诊方面具有重要作用,并且是性腺切除术和切除与指定性别相反结构的有效方法。

相似文献

1
Use of laparoscopy in intersex patients.腹腔镜检查在两性畸形患者中的应用。
J Urol. 1995 Sep;154(3):1193-6.
2
The use of laparoscopy in intersex patients.腹腔镜检查在两性畸形患者中的应用。
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Laparoscopy in endocrine and genetic disorders of the gonads.腹腔镜检查在性腺内分泌和遗传性疾病中的应用。
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The laparoscopic management of intersex patients: the preferred approach.两性畸形患者的腹腔镜治疗:首选方法。
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Patients with disorders of sex development (DSD) at risk of gonadal tumour development: management based on laparoscopic biopsy and molecular diagnosis.性发育障碍(DSD)患者有发生性腺肿瘤的风险:基于腹腔镜活检和分子诊断的管理。
BJU Int. 2012 Dec;110(11 Pt C):E958-65. doi: 10.1111/j.1464-410X.2012.11181.x. Epub 2012 Apr 30.
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[Diagnosis and management of patients with sex differentiation disorders: experience at the Unit of Medical Genetics of the University of Zulia, Maracaibo, Venezuela].[性分化障碍患者的诊断与管理:委内瑞拉马拉开波苏利亚大学医学遗传学单位的经验]
Invest Clin. 1998 Dec;39(4):273-92.
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Androgen insensitivity syndrome with serous gonadal cyst.雄激素不敏感综合征伴浆液性性腺囊肿
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Bilateral laparoscopic gonadectomy in a patient with complete androgen insensitivity. A case report.双侧腹腔镜性腺切除术治疗完全性雄激素不敏感综合征患者。病例报告。
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