Leibovitch I, Baniel J, Foster R S, Donohue J P
Department of Urology, Indiana University School of Medicine, Indianapolis, USA.
J Urol. 1995 Sep;154(3):935-9.
The clinical implications of procedural deviations during orchiectomy for nonseminomatous testis cancer were evaluated.
A retrospective review was done of 78 of 1,708 patients (4.6%) with nonseminomatous testis cancer who presented to our university following scrotal violation.
A total of 56 patients (71.8%) underwent hemi-scrotectomy as part of treatment. A tumor was found in 6 of 56 hemi-scrotectomy specimens (10.7%) and 3 showed local recurrence. Of the 78 patients 5 (6.4%) had local recurrence, while 1 of 30 (3.3%) with scrotal specimens negative for tumor had recurrence in the groin. No patient treated by chemotherapy had local recurrence.
Scrotal violation was associated with an increased risk for local recurrence mainly when a residual tumor in the scrotectomy specimen was found. The role of hemi-scrotectomy to avoid of local or systemic relapse is debatable.
评估非精原细胞瘤性睾丸癌睾丸切除术中操作偏差的临床意义。
对我校收治的1708例阴囊受侵的非精原细胞瘤性睾丸癌患者中的78例(4.6%)进行回顾性研究。
共有56例患者(71.8%)接受了半阴囊切除术作为治疗的一部分。在56例半阴囊切除标本中有6例(10.7%)发现肿瘤,3例出现局部复发。78例患者中有5例(6.4%)出现局部复发,而30例阴囊标本肿瘤阴性的患者中有1例(3.3%)腹股沟复发。接受化疗的患者均无局部复发。
阴囊受侵与局部复发风险增加相关,主要是在阴囊切除标本中发现残留肿瘤时。半阴囊切除术在避免局部或全身复发方面的作用存在争议。