[Synergism of ciprofloxacin and roxithromycin to Pseudomonas aeruginosa biofilm].

Synergism of ciprofloxacin (CPFX) and roxithromycin (RXM) to bacterial biofilms formed by Pseudomonas aeruginosa was investigated. Measurement of antibacterial activities and morphological observation with a scanning electron-microscope suggested that RXM eradicated the biofilms by unknown mechanism and thereby enhanced the bactericidal activity of CPFX to P. aeruginosa in biofilms.