Kondo D, Kita Y
Department of Chest Surgery, Shizuoka Saiseikai General Hospital, Japan.
Kyobu Geka. 1995 Jul;48(7):592-4.
We have successfully treated MRSA empyema after right pneumonectomy by the closed drainage and irrigation alone. The patient was a 70-year-old male who had received right pneumonectomy for p-III a squamous cell carcinoma originating in the right upper lobe bronchus. The operation wound was infected on the 6th postoperative day and became pleural fistula and finally MRSA empyema was developed on the 10th postoperative day. The chest drainage and irrigation of the infected pneumonectomy space with physiological saline containing antiseptic povidone iodine (Isodine) were performed 3 times a day for 14 days, however, the empyema was not cured completely. In addition, nausea and vomiting considered as the side effect of Isodine severely appeared. Therefore the antiseptic agent was exchanged to vancomycin hydrochloride from povidone iodine. Empyema space became sterile 4 days after the exchange and the drainage tube was removed 7 days after sterilization. Further empyema has not been developed for 8 months. We discussed the method and antiseptic agents in irrigation of empyema space.
我们仅通过闭式引流和冲洗就成功治疗了右肺切除术后的耐甲氧西林金黄色葡萄球菌(MRSA)脓胸。患者为一名70岁男性,因起源于右上叶支气管的p-III a期鳞状细胞癌接受了右肺切除术。术后第6天手术伤口感染,形成了胸膜瘘,最终在术后第10天发展为MRSA脓胸。每天用含抗菌聚维酮碘(碘伏)的生理盐水对感染的肺切除腔进行3次胸腔引流和冲洗,持续14天,但脓胸并未完全治愈。此外,严重出现了被认为是碘伏副作用的恶心和呕吐。因此,抗菌剂从聚维酮碘换成了盐酸万古霉素。更换后4天脓胸腔变为无菌,灭菌后7天拔除引流管。8个月来未再发生进一步的脓胸。我们讨论了脓胸腔冲洗的方法和抗菌剂。