Calbindin D28k mRNA in hippocampus, superior temporal gyrus and cerebellum: comparison between control and Alzheimer disease subjects.

作者信息

Maguire-Zeiss K A, Li Z W, Shimoda L M, Hamill R W

机构信息

Department of Neurology, University of Rochester School of Medicine and Dentistry, NY 14642, USA.

出版信息

Brain Res Mol Brain Res. 1995 Jun;30(2):362-6. doi: 10.1016/0169-328x(95)00035-q.

To further investigate the role of calbindin D28k in Alzheimer's disease (AD); hippocampus, superior temporal gyrus and cerebellum from control and AD cases were examined by quantitative in situ hybridization. We report here a decrease in CaBD28k mRNA in the CA2 region of AD hippocampus compared to control subjects. There were no significant differences between AD and control subjects in the other regions studied.