海马体、颞上回和小脑中的钙结合蛋白D28k信使核糖核酸：对照者与阿尔茨海默病患者的比较
Calbindin D28k mRNA in hippocampus, superior temporal gyrus and cerebellum: comparison between control and Alzheimer disease subjects.
作者信息
Maguire-Zeiss K A, Li Z W, Shimoda L M, Hamill R W
机构信息
Department of Neurology, University of Rochester School of Medicine and Dentistry, NY 14642, USA.
出版信息
Brain Res Mol Brain Res. 1995 Jun;30(2):362-6. doi: 10.1016/0169-328x(95)00035-q.
To further investigate the role of calbindin D28k in Alzheimer's disease (AD); hippocampus, superior temporal gyrus and cerebellum from control and AD cases were examined by quantitative in situ hybridization. We report here a decrease in CaBD28k mRNA in the CA2 region of AD hippocampus compared to control subjects. There were no significant differences between AD and control subjects in the other regions studied.
为进一步研究钙结合蛋白D28k在阿尔茨海默病（AD）中的作用；通过定量原位杂交检测了对照组和AD患者的海马、颞上回和小脑。我们在此报告，与对照组相比，AD海马CA2区的CaBD28k mRNA减少。在研究的其他区域，AD患者和对照组之间没有显著差异。
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