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复发性和转移性前列腺癌的单克隆抗体成像

Monoclonal antibody imaging of recurrent and metastatic prostate cancer.

作者信息

Burgers J K, Hinkle G H, Haseman M K

机构信息

Urology Surgeons Inc, Riverside Hospital, Columbus, OH 43214-3901, USA.

出版信息

Semin Urol. 1995 May;13(2):103-12.

PMID:7638467
Abstract

In summary, this agent is safe for administration and more accurate than any currently available imaging modality for the detection of extraprostatic metastases. This agent is still under investigation and some day may aid urologists in the evaluation of prostate cancer by improving preoperative staging and demonstration of advanced disease and postoperative localization of recurrent disease. Improved staging and localization will reduce unnecessary tests and treatment that will lead to reduced morbidity, better management, earlier detection, and intervention in advanced disease and improved cost-effectiveness.

摘要

总之,这种制剂给药安全,在检测前列腺外转移方面比任何现有成像方式都更准确。该制剂仍在研究中,未来某天可能会通过改善术前分期、显示晚期疾病以及术后复发病灶的定位,帮助泌尿科医生评估前列腺癌。改进分期和定位将减少不必要的检查和治疗,从而降低发病率、改善治疗管理、更早发现和干预晚期疾病,并提高成本效益。

相似文献

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Monoclonal antibody imaging of recurrent and metastatic prostate cancer.复发性和转移性前列腺癌的单克隆抗体成像
Semin Urol. 1995 May;13(2):103-12.
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Multicenter radioimmunoscintigraphic evaluation of patients with prostate carcinoma using indium-111 capromab pendetide.使用铟-111 卡妥索单抗对前列腺癌患者进行多中心放射免疫闪烁显像评估。
Cancer. 1998 Aug 15;83(4):739-47.
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Indium-111 capromab pendetide in the management of recurrent prostate cancer.铟-111 卡波单抗喷地肽在复发性前列腺癌治疗中的应用
Expert Rev Anticancer Ther. 2008 Feb;8(2):175-81. doi: 10.1586/14737140.8.2.175.
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Utility of capromab pendetide (ProstaScint) imaging in the management of prostate cancer.卡普睾酮(ProstaScint)成像在前列腺癌管理中的应用。
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Prostate cancer abdominal metastases detected with indium-111 capromab pendetide.用铟-111卡普单抗检测到的前列腺癌腹部转移灶。
J Nucl Med. 1998 Apr;39(4):650-2.
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Monoclonal antibody scan holds promise for prostate cancer staging.单克隆抗体扫描对前列腺癌分期有帮助。
J Nucl Med. 1996 Apr;37(4):11N-12N, 15N.
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The dual-isotope ProstaScint imaging procedure: clinical experience and staging results in 145 patients.双同位素前列腺闪烁成像检查法:145例患者的临床经验及分期结果
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Update on magnetic resonance imaging, ProstaScint, and novel imaging in prostate cancer.前列腺癌的磁共振成像、前列腺闪烁显像及新型成像技术的最新进展
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Synergistic value of single-photon emission computed tomography/computed tomography fusion to radioimmunoscintigraphic imaging of prostate cancer.单光子发射计算机断层扫描/计算机断层扫描融合对前列腺癌放射免疫闪烁成像的协同价值。
Semin Nucl Med. 2007 Jan;37(1):17-28. doi: 10.1053/j.semnuclmed.2006.07.002.

引用本文的文献

1
Comparison of prostate-specific membrane antigen ligands in clinical translation research for diagnosis of prostate cancer.比较用于前列腺癌诊断的临床转化研究中的前列腺特异性膜抗原配体。
Cancer Rep (Hoboken). 2019 Aug;2(4):e1169. doi: 10.1002/cnr2.1169. Epub 2019 Apr 2.
2
Capromab pendetide. A review of its use as an imaging agent in prostate cancer.卡普睾酮。其作为前列腺癌成像剂的应用综述。
Drugs Aging. 1998 Apr;12(4):293-304. doi: 10.2165/00002512-199812040-00004.