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[胃平滑肌肉瘤和平滑肌母细胞瘤]

[Gastric leiomyosarcomas and leiomyoblastomas].

作者信息

Sobrino Cossio S R, García Guerrero V A, Pérez Torres E, Abdo Francis J M, Bernal Sahagún F, Aristi Urista G

机构信息

Hospital General de México, SS., Servicio de Gastroenterología.

出版信息

Rev Gastroenterol Mex. 1995 Jan-Mar;60(1):12-6.

PMID:7638526
Abstract

The authors review the cases with smooth muscle tumors of the stomach (SMTS), excluding the leiomyomas, at the Mexico's General Hospital in a period of 5 years. They found 8 cases in women and 3 in men, with 51.3 years average. The average of evolution of symptoms was 5 months, prevailing: anaemia, digestive bleeding and abdominal pain. Barium radiology and endoscopy guided to the diagnosis. The tumors were located 7 at the fundus, 3 at the body and one at the gastric antrum. The size oscillated between 1.5-28 cm., average 8 cm. Endoscopic specimens were positive in 2/7 cases and cytologic samples were negative in all cases. Eight tumors were leiomyosarcomas (LMS) and 3 were leiomyoblastomas (LMB); the histologic criteria in order to differentiate them was based on the number of mitosis for 50 fields (50 csf), the size and their hypercellularity. A patient died before being operated. Two cases were subjected to emergency surgery, and died after that. In the cases treated with elective surgery the authors performed subtotal gastrectomy with major omentectomy in 4 and surgical resection of the tumor in the remaining 4 patients. The mortality rate for surgery was 27.2%.

摘要

作者回顾了墨西哥总医院5年间收治的胃平滑肌瘤(不包括平滑肌瘤)病例。他们发现8例女性患者和3例男性患者,平均年龄51.3岁。症状平均演变时间为5个月,主要症状为贫血、消化道出血和腹痛。钡剂造影和内镜检查有助于诊断。肿瘤位于胃底7例,胃体3例,胃窦1例。大小在1.5 - 28厘米之间,平均8厘米。7例中有2例内镜标本呈阳性,所有病例的细胞学样本均为阴性。8例为平滑肌肉瘤(LMS),3例为平滑肌瘤(LMB);区分它们的组织学标准基于50个视野(50 csf)的有丝分裂数量、大小及其细胞增多情况。1例患者在手术前死亡。2例接受了急诊手术,术后死亡。在接受择期手术的病例中,作者对4例患者进行了胃大部切除术并切除大网膜,其余4例患者进行了肿瘤手术切除。手术死亡率为27.2%。

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