Tareeva I E, Kozlovskaia L V, Kabaenkova G S, Kozlovskaia N L
Ter Arkh. 1995;67(5):9-13.
60 patients with lupus nephritis (LN) were examined for frequency of thrombocytopenia, role of IgG and IgM antibodies to cardiolipin (AC), antithrombocytic antibodies (AA) and anaerobic platelet metabolism. Thrombocytopenia occurred in 28 (46.7%) patients, it was 2 times more frequent in active LN patients with AC than in those free of AC. AA were recorded in 36.6% of patients (32.2% versus 37.5% for patients with thrombocytopenia and free of it, respectively). In active LN platelet activity and metabolism became enhanced. Genesis of thrombocytopenia in various LN forms may be induced by different mechanisms.
对60例狼疮性肾炎（LN）患者进行了血小板减少症的发生率、抗心磷脂（AC）的IgG和IgM抗体、抗血小板抗体（AA）以及血小板无氧代谢作用的检查。28例（46.7%）患者出现血小板减少症，伴有AC的活动性LN患者中血小板减少症的发生率是无AC患者的2倍。36.6%的患者检测到AA（血小板减少症患者和无血小板减少症患者分别为32.2%和37.5%）。在活动性LN中，血小板活性和代谢增强。不同LN形式中血小板减少症的发生可能由不同机制诱发。
