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[神经元迁移障碍。放射学和临床方面]

[Neuronal migration disorders. Radiological and clinical aspects].

作者信息

Orderud W J, Skjeldal O H, Strømme P

机构信息

Nevroradiologisk seksjon, Røntgen-Radiumavdelingen, Rikshospitalet, Oslo.

出版信息

Tidsskr Nor Laegeforen. 1995 Jun 20;115(16):1952-6.

PMID:7638849
Abstract

Neuronal migration disorders can cause congenital cerebral malformations during the third and fourth months of gestation. They are usually classified as agyria, pachygyria, schizencephaly, polymicrogyria and heterotopic gray matter. The best diagnostic tool for detecting neuronal migration disorders is magnetic resonance imaging (MRI). Frequently, the migration disorders are associated with epilepsy, psychomotor retardation and cerebral palsy, and patients with these symptoms should always be investigated by cerebral MRI. In this article we discuss radiologic and clinical aspects in the case of six persons with different categories of migration disorders.

摘要

神经元迁移障碍可在妊娠第三和第四个月期间导致先天性脑畸形。它们通常被分类为无脑回畸形、巨脑回畸形、脑裂畸形、多小脑回畸形和灰质异位。检测神经元迁移障碍的最佳诊断工具是磁共振成像(MRI)。迁移障碍常与癫痫、精神运动发育迟缓及脑瘫相关,有这些症状的患者应始终接受脑部MRI检查。在本文中,我们讨论了6例不同类型迁移障碍患者的放射学和临床情况。

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