Río J, Montalbán J, Pujadas F, Alvarez-Sabín J, Rovira A, Codina A
Servei de Neurología, Hospital General Universitari Vall d'Hebron, Barcelona, Spain.
Acta Neurol Scand. 1995 May;91(5):377-81. doi: 10.1111/j.1600-0404.1995.tb07024.x.
Asterixis is an uncommon sign in structural central nervous system disorders. When asterixis is present, one cannot rule out the possibility of a focal lesion, but it is almost always due to a metabolic encephalopathy.
In the last five years all patients with uni- or bilateral neurologic asterixis attended in our hospital have been studied. Cerebral computed tomogram or magnetic resonance imaging was performed in all patients with uni or bilateral asterixis.
We describe 45 patients with different forms of structural cerebral pathology who presented unilateral (37 patients) or bilateral (8 patients) asterixis not associated to either toxic or metabolic disorder. Central nervous system ischemic or hemorrhagic disorders were found to be the most frequent causes of asterixis (95.5%) and the thalamus the most frequent localization for unilateral asterixis to result (54%).
Bilateral asterixis is not always associated with toxic or metabolic disorders and it may be a sign of some structural neurologic alterations. A good correlation was found between the presence of unilateral asterixis and structural intracranial disease.
扑翼样震颤在结构性中枢神经系统疾病中是一种不常见的体征。当出现扑翼样震颤时，不能排除局灶性病变的可能性，但几乎总是由代谢性脑病引起。
在过去五年中，我们对我院收治的所有单侧或双侧神经性扑翼样震颤患者进行了研究。对所有单侧或双侧扑翼样震颤患者均进行了脑部计算机断层扫描或磁共振成像检查。
我们描述了45例患有不同形式结构性脑部病变的患者，他们出现了单侧（37例）或双侧（8例）扑翼样震颤，且与中毒或代谢紊乱无关。中枢神经系统缺血性或出血性疾病是扑翼样震颤最常见的原因（95.5%），丘脑是单侧扑翼样震颤最常见的发生部位（54%）。
双侧扑翼样震颤并不总是与中毒或代谢紊乱相关，它可能是某些结构性神经改变的体征。单侧扑翼样震颤的出现与颅内结构性疾病之间存在良好的相关性。
