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[巨大肺血栓栓塞继发右心室急性梗死]

[Acute infarct of the right ventricle secondary to a massive pulmonary thromboembolism].

作者信息

Jerjes Sánchez C, Gutiérrez-Fajardo P, Ramírez-Rivera A, García-Mollinedo M de L, Hernández Chávez G

机构信息

Servicio de Urgencias, Hospital de Cardiologiá, Centro Médico Nacional, Siglo XXI, IMSS, México, D.F.

出版信息

Arch Inst Cardiol Mex. 1995 Jan-Feb;65(1):65-73.

PMID:7639598
Abstract

The hemodynamic and cardiovascular responses to a massive pulmonary embolism are: severe pulmonary hypertension, right ventricular failure and cardiogenic shock. The irreversible state of the latest condition and mortality could be due to a secondary right ventricle myocardial infarction, an entity which was first described in 1949. We report a necropsy case with massive pulmonary embolism and as a relevant finding a recent right ventricular myocardial infarction without significant obstructive coronary lesions. The relevance of right ventricle myocardial infarction as a major risk factor for mortality, its clinical and hemodynamic profile as well as the ischemic phenomena, are analyzed. It is emphasized also the importance of an early lysis of thrombus to rescue myocardium and to preserve right ventricle viability. This could be the first case reported in Mexico, in which the relationship between massive pulmonary embolism and right ventricle myocardial infarction is demonstrated as a determinant factor for mortality.

摘要

大面积肺栓塞的血流动力学和心血管反应包括

严重肺动脉高压、右心室衰竭和心源性休克。最新病情的不可逆状态及死亡率可能归因于继发性右心室心肌梗死,这一实体于1949年首次被描述。我们报告一例尸检病例,该病例存在大面积肺栓塞,且有一项相关发现,即近期发生右心室心肌梗死但无明显阻塞性冠状动脉病变。分析了右心室心肌梗死作为主要死亡风险因素的相关性、其临床和血流动力学特征以及缺血现象。还强调了早期溶栓以挽救心肌和维持右心室活力的重要性。这可能是墨西哥报道的首例病例,其中大面积肺栓塞与右心室心肌梗死之间的关系被证明是死亡的决定性因素。

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