Szivek J A, Thompson J D, Benjamin J B
Department of Surgery, University of Arizona, Tucson 85724, USA.
J Appl Biomater. 1995 Summer;6(2):125-8. doi: 10.1002/jab.770060207.
Porous polyurethane foams were prepared from Daro foam components with a range of mechanical properties to simulate human trabecular bone. Ratios of 10.0:5.0, 10.0:7.9, and 10.0:10.0 isocyanate to resin were mixed, cured, and cut into cubes. Properties were determined from uniaxial compression to 50% of the original cube height at a strain rate of 1.2 mm/s. Electron microscopy was used to characterize the foam structure. Average compressive yield stress values, ultimate compressive stresses, and elastic moduli ranged from 4.44 to 2.79, 5.61 to 3.28, and 134.0 to 110.1 MPa, respectively, for the three formulations. The foam materials showed a similar morphology of spherical bubbles, and the average bubble size tended to decrease as the ratio of isocyanate to resin increased even though the bubble size differences were not statistically significant. The results indicate that large blocks of foam can be prepared with consistent mechanical properties simulating a range of trabecular bone properties so that implants can be tested for various patient populations.
采用一系列具有不同力学性能的达罗泡沫成分制备多孔聚氨酯泡沫，以模拟人体松质骨。将异氰酸酯与树脂的比例分别为10.0:5.0、10.0:7.9和10.0:10.0的混合物进行混合、固化，然后切成正方体。在应变速率为1.2 mm/s的条件下，通过单轴压缩至原始正方体高度的50%来测定性能。使用电子显微镜对泡沫结构进行表征。三种配方的平均压缩屈服应力值、极限压缩应力和弹性模量分别为4.44至2.79 MPa、5.61至3.28 MPa和134.0至110.1 MPa。泡沫材料呈现出类似的球形气泡形态，尽管气泡尺寸差异无统计学意义，但随着异氰酸酯与树脂比例的增加，平均气泡尺寸趋于减小。结果表明，可以制备出具有一致力学性能的大块泡沫，模拟一系列松质骨性能，从而能够针对不同患者群体对植入物进行测试。
