Chen W, He Y, Lin Z X
Longhua Hospital, Shanghai University of TCM.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 May;15(5):271-3.
There was evidence that abnormal left ventricular diastolic function was common in patients with coronary heart disease which led to symptoms such as dyspnea on exertion, distress in chest etc, even overt congestive heart failure. The changes of left ventricular diastolic function were examined with pulsed doppler echocardiography as well as of clinical symptoms, signs, electrocardiographic findings and plasma lipoprotein after Shuxinyin (SXY) therapy in 31 patients with coronary heart disease and abnormal left ventricular diastolic function. The SXY mainly consists of medicinal herbs capable of tonifying Qi and Yin. After treatment for one month the symptoms, signs and ECG were improved, the symptomatic effective rate was 87.1%. Plasma lipoprotein was reduced (P < 0.05). The main changes in doppler echocardiography were as follows. The peak of E wave, the area of E wave and Dec rate increased significantly (P < 0.01). The ratio of A wave peak to E wave peak was decreased. The changes in peak of A wave, the area of A wave and time index were insignificant (P > 0.05). It was concluded that SXY mainly improved the early left ventricular diastolic functions, increased the peak velocity and volume of rapid left ventricular filling blood flow during the early diastole, and thus alleviated symptoms as well as ECG findings.
有证据表明，冠心病患者左心室舒张功能异常较为常见，这会导致诸如劳力性呼吸困难、胸痛等症状，甚至出现明显的充血性心力衰竭。应用脉冲多普勒超声心动图检查31例冠心病伴左心室舒张功能异常患者经舒心饮（SXY）治疗后左心室舒张功能的变化，以及临床症状、体征、心电图表现和血浆脂蛋白的变化。舒心饮主要由益气养阴的草药组成。治疗1个月后，症状、体征和心电图均有改善，症状有效率为87.1%。血浆脂蛋白降低（P<0.05）。多普勒超声心动图的主要变化如下：E波峰值、E波面积和减速速率显著增加（P<0.01）。A波峰值与E波峰值之比降低。A波峰值、A波面积和时间指数的变化不显著（P>0.05）。结论：舒心饮主要改善左心室早期舒张功能，增加舒张早期左心室快速充盈血流的峰值速度和容积，从而缓解症状和心电图表现。
