• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Three-dimensional architecture of the skeletal muscle ryanodine receptor.

作者信息

Wagenknecht T, Radermacher M

机构信息

Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201-0509, USA.

出版信息

FEBS Lett. 1995 Aug 1;369(1):43-6. doi: 10.1016/0014-5793(95)00581-s.

DOI:10.1016/0014-5793(95)00581-s
PMID:7641882
Abstract

Recent advances in determining the three-dimensional architecture of the skeletal muscle ryanodine receptor/calcium release channel (RyR) by cryo-electron microscopy and three-dimensional reconstruction are discussed. The tetrameric receptor is characterized by a large 4-fold symmetric cytoplasmic assembly that consists of many domains separated by solvent-containing crevices and holes. Experimental evidence suggests that at least one regulatory ligand, calmodulin, binds to sites on the cytoplasmic assembly that are at least 10 nanometers from the transmembrane channel.

摘要

相似文献

1
Three-dimensional architecture of the skeletal muscle ryanodine receptor.
FEBS Lett. 1995 Aug 1;369(1):43-6. doi: 10.1016/0014-5793(95)00581-s.
2
Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle.骨骼肌钙释放通道/雷诺丁受体的冷冻电子显微镜观察及三维重建
J Cell Biol. 1994 Oct;127(2):411-23. doi: 10.1083/jcb.127.2.411.
3
Ryanodine receptors: structure and macromolecular interactions.
Curr Opin Struct Biol. 1997 Apr;7(2):258-65. doi: 10.1016/s0959-440x(97)80034-6.
4
Localization of calmodulin binding sites on the ryanodine receptor from skeletal muscle by electron microscopy.通过电子显微镜对骨骼肌兰尼碱受体上钙调蛋白结合位点的定位
Biophys J. 1994 Dec;67(6):2286-95. doi: 10.1016/S0006-3495(94)80714-3.
5
Cryoelectron microscopy resolves FK506-binding protein sites on the skeletal muscle ryanodine receptor.冷冻电子显微镜解析骨骼肌兰尼碱受体上的FK506结合蛋白位点。
Biophys J. 1996 Apr;70(4):1709-15. doi: 10.1016/S0006-3495(96)79733-3.
6
Cryo-EM of the native structure of the calcium release channel/ryanodine receptor from sarcoplasmic reticulum.肌浆网钙释放通道/雷诺丁受体天然结构的冷冻电镜研究
Biophys J. 1992 Apr;61(4):936-40. doi: 10.1016/S0006-3495(92)81900-8.
7
Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel.
Nat Struct Biol. 1995 Jan;2(1):18-24. doi: 10.1038/nsb0195-18.
8
Interaction of S100A1 with the Ca2+ release channel (ryanodine receptor) of skeletal muscle.S100A1与骨骼肌的Ca2+释放通道（雷诺丁受体）的相互作用。
Biochemistry. 1997 Sep 23;36(38):11496-503. doi: 10.1021/bi970160w.
9
Locations of calmodulin and FK506-binding protein on the three-dimensional architecture of the skeletal muscle ryanodine receptor.钙调蛋白和FK506结合蛋白在骨骼肌兰尼碱受体三维结构上的定位。
J Biol Chem. 1997 Dec 19;272(51):32463-71. doi: 10.1074/jbc.272.51.32463.
10
Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.缺乏1型和3型兰尼碱受体的突变小鼠骨骼肌的功能和形态学特征
J Physiol. 1997 Jun 1;501 ( Pt 2)(Pt 2):305-12. doi: 10.1111/j.1469-7793.1997.305bn.x.

引用本文的文献

1
Ryanodine Receptor Structure and Function in Health and Disease.健康与疾病状态下的兰尼碱受体结构与功能
Subcell Biochem. 2018;87:329-352. doi: 10.1007/978-981-10-7757-9_11.
2
Single-particle cryo-EM of the ryanodine receptor channel in an aqueous environment.在水性环境中对兰尼碱受体通道进行单颗粒冷冻电镜研究。
Eur J Transl Myol. 2015;25(1):4803. doi: 10.4081/ejtm.2015.4803.
3
Control of IsAHP in mouse hippocampus CA1 pyramidal neurons by RyR3-mediated calcium-induced calcium release.通过RyR3介导的钙诱导钙释放对小鼠海马体CA1锥体神经元中IsAHP的调控。
Pflugers Arch. 2007 Nov;455(2):297-308. doi: 10.1007/s00424-007-0277-4. Epub 2007 Jun 12.
4
The three-dimensional structure of complex I from Yarrowia lipolytica: a highly dynamic enzyme.解脂耶氏酵母中复合物I的三维结构：一种高度动态的酶。
J Struct Biol. 2006 Jun;154(3):269-79. doi: 10.1016/j.jsb.2006.02.011. Epub 2006 Mar 24.
5
Topology of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum (RyR1).骨骼肌肌浆网Ca2+释放通道（RyR1）的拓扑结构
Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16725-30. doi: 10.1073/pnas.012688999. Epub 2002 Dec 16.
6
Amino acid residues 4425-4621 localized on the three-dimensional structure of the skeletal muscle ryanodine receptor.位于骨骼肌兰尼碱受体三维结构上的氨基酸残基4425 - 4621。
Biophys J. 2000 Mar;78(3):1349-58. doi: 10.1016/S0006-3495(00)76689-6.
7
Comparison of properties of Ca2+ release channels between rabbit and frog skeletal muscles.兔与蛙骨骼肌中Ca2+释放通道特性的比较。
Mol Cell Biochem. 1999 Jan;190(1-2):191-201.
8
Subconductance states in single-channel activity of skeletal muscle ryanodine receptors after removal of FKBP12.去除FKBP12后骨骼肌兰尼碱受体单通道活性中的亚电导状态
Biophys J. 1997 Jan;72(1):146-62. doi: 10.1016/S0006-3495(97)78654-5.
9
Cryoelectron microscopy resolves FK506-binding protein sites on the skeletal muscle ryanodine receptor.冷冻电子显微镜解析骨骼肌兰尼碱受体上的FK506结合蛋白位点。
Biophys J. 1996 Apr;70(4):1709-15. doi: 10.1016/S0006-3495(96)79733-3.