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Immunocytochemistry of annulate lamellae: potential cell biological markers for studies of cell differentiation and pathology.

作者信息

Cordes V C, Gajewski A, Stumpp S, Krohne G

机构信息

Institute for Cell and Tumor Biology, German Cancer Research Center, Heidelberg.

出版信息

Differentiation. 1995 Apr;58(4):307-12. doi: 10.1046/j.1432-0436.1995.5840307.x.

DOI:10.1046/j.1432-0436.1995.5840307.x
PMID:7641981
Abstract

We have generated specific antibodies recognizing different proteins of the nuclear pore complex and have applied them for the biochemical and microscopical analysis of annulate lamellae (AL). Using the example of the Xenopus laevis oocyte we show that the combined application of such antibodies to different components of the nuclear pore complex allows the unequivocal identification of AL. We propose to use such antibodies in immunostaining light microscopy for detecting AL as a diagnostic marker in a diversity of cell types, including those with pathological alterations in AL frequency and distribution.

摘要

相似文献

1
Immunocytochemistry of annulate lamellae: potential cell biological markers for studies of cell differentiation and pathology.
Differentiation. 1995 Apr;58(4):307-12. doi: 10.1046/j.1432-0436.1995.5840307.x.
2
High content of a nuclear pore complex protein in cytoplasmic annulate lamellae of Xenopus oocytes.非洲爪蟾卵母细胞胞质环孔片层中核孔复合体蛋白含量高。
Eur J Cell Biol. 1995 Nov;68(3):240-55.
3
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Mediators of nuclear protein import target karyophilic proteins to pore complexes of cytoplasmic annulate lamellae.核蛋白输入的介质将亲核蛋白靶向至细胞质环孔板的孔复合体。
Exp Cell Res. 1997 Dec 15;237(2):419-33. doi: 10.1006/excr.1997.3806.
5
An integral membrane protein from the nuclear pore complex is also present in the annulate lamellae: implications for annulate lamella formation.核孔复合体中的一种整合膜蛋白也存在于环状片层中：对环状片层形成的影响。
Exp Cell Res. 2000 Aug 25;259(1):180-90. doi: 10.1006/excr.2000.4935.
6
Intranuclear membranes (vesicles, lamellae, annulate lamellae) in oocytes of the ascidian, Styela partita.柄海鞘卵母细胞中的核内膜（囊泡、片层、环孔片层）。
J Submicrosc Cytol. 1983 Jul;15(3):773-85.
7
Nuclear pore complex assembly studied with a biochemical assay for annulate lamellae formation.通过用于环状片层形成的生化分析研究核孔复合体组装。
J Cell Biol. 1995 Jun;129(6):1459-72. doi: 10.1083/jcb.129.6.1459.
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An antibody against a glycosylated integral membrane protein of the Xenopus laevis nuclear pore complex: a tool for the study of pore complex membranes.
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Domain-specific disassembly and reassembly of nuclear membranes during mitosis.有丝分裂过程中核膜的特定结构域拆卸与重新组装
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Intranuclear membrane structure formations by CaaX-containing nuclear proteins.含CaaX的核蛋白形成的核内膜结构
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