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[细菌性心内膜炎的二尖瓣修复手术]

[Reparative surgery of the mitral valve in bacterial endocarditis].

作者信息

Fucci C, La Canna G, Berra P, Pardini A, Sandrelli L, Alfieri O

机构信息

II Divisione di Cardiochirurgia, Spedali Civili e Università degli Studi di Brescia.

出版信息

G Ital Cardiol. 1995 Mar;25(3):335-40.

PMID:7642039
Abstract

INTRODUCTION

Short and long-term results of valve repair for pure mitral insufficiency resulting from native valve endocarditis are reported in 28 consecutive patients with a mean age of 55 years (range 18-74).

METHODS

Six patients had acute endocarditis, with positive blood cultures in three of them. The mean time between onset of endocarditis symptoms and operation was 23 days in patients with acute endocarditis and 4.6 years in patients with healed endocarditis. Preoperatively, 87% of the patients were in NYHA class III. Indications for operation were heart failure (24 patients) and uncontrolled sepsis (4 patients). Mitral valvuloplasty was combined with other procedures in 4 patients. There was previous underlying valve pathology in 75%.

RESULTS

Mitral repair was performed according to the techniques proposed by Carpentier; in 2 cases we used an original technique consisting of a double-orifice repair. Only one patient died in the hospital (operative mortality: 3.5%). By actuarial methods 96% of the patients were alive 6 years postoperatively. During the follow-up period there was no recurrence of endocarditis and no reoperation for valvular insufficiency. Ninety-three per cent of the patients were in NYHA class I or II.

CONCLUSIONS

We conclude that mitral valve repair for insufficiency resulting from bacterial endocarditis is possible in acute and healed disease, has a low operative mortality and has resulted in patients free of recurrent infection. Mitral valve repair is an attractive alternate to valve replacement in bacterial endocarditis.

摘要

引言

报道了连续28例平均年龄55岁(18 - 74岁)因原发性瓣膜性心内膜炎导致单纯二尖瓣关闭不全患者行瓣膜修复的短期和长期结果。

方法

6例患者患有急性心内膜炎,其中3例血培养阳性。急性心内膜炎患者心内膜炎症状发作至手术的平均时间为23天,愈合性心内膜炎患者为4.6年。术前,87%的患者为纽约心脏协会(NYHA)心功能Ⅲ级。手术指征为心力衰竭(24例)和无法控制的败血症(4例)。4例患者二尖瓣成形术与其他手术联合进行。75%的患者既往有潜在瓣膜病变。

结果

二尖瓣修复按照Carpentier提出的技术进行;2例患者我们采用了一种原创技术,即双孔修复。仅1例患者死于医院(手术死亡率:3.5%)。通过精算方法,96%的患者术后6年存活。随访期间无感染性心内膜炎复发,也无因瓣膜关闭不全再次手术。93%的患者为NYHA心功能Ⅰ级或Ⅱ级。

结论

我们得出结论,对于细菌性心内膜炎导致的二尖瓣关闭不全,在急性和愈合性疾病中均可进行二尖瓣修复,手术死亡率低,且患者无反复感染。在细菌性心内膜炎中,二尖瓣修复是瓣膜置换的一种有吸引力的替代方法。

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