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[30年二尖瓣脱垂——哪些情况依然未变?]

[30 years mitral valve prolapse--what has stayed the same?].

作者信息

Rampp T, von Essen R

机构信息

Klinik für Innere Medizin, Stiftsklinik Augustinum, München.

出版信息

Fortschr Med. 1995 Jun 20;113(17):257-62.

PMID:7642157
Abstract

As a Result of echocardiographic diagnostic criteria that took too little account of underlying pathology, mitral valve prolapse has, in the past, been diagnosed far too frequently, and has been associated with commonly occurring unspecific symptoms (mitral valve prolapse syndrome). The results of epidemiological studies have led to a new definition of diagnostic criteria. The diagnosis mitral valve prolapse is established in the first instance by auscultation. Echocardiography supports the diagnosis, provides information about the prognosis, and, with a high level of reliability, detects complications. Major complications of this condition are endocarditis and mitral valve insufficiency, as also--less well documented--cerebral embolism and sudden heart death. Particularly at risk of developing complications are those patients with a systolic murmur reflecting an already present mitral valve insufficiency. This patient group must be monitored for progressive mitral insufficiency and, in the presence of relevant exposure, requires endocarditis prophylaxis.

摘要

由于超声心动图诊断标准对潜在病理情况考虑不足,过去二尖瓣脱垂的诊断过于频繁,且常与常见的非特异性症状(二尖瓣脱垂综合征)相关。流行病学研究结果促使了诊断标准的重新定义。二尖瓣脱垂的诊断首先通过听诊确立。超声心动图支持诊断,提供预后信息,并能高度可靠地检测并发症。该病症的主要并发症是心内膜炎和二尖瓣关闭不全,还有——记录较少的——脑栓塞和心脏性猝死。出现反映已有二尖瓣关闭不全的收缩期杂音的患者尤其有发生并发症的风险。必须对这一患者群体监测二尖瓣关闭不全的进展情况,并且在有相关暴露的情况下,需要进行心内膜炎预防。

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