Miedzybrodzka Z, Semper J, Shackley P, Abdalla M, Donaldson C
University of Aberdeen, Department of Obstetrics and Gynaecology, Aberdeen Maternity Hospital, Foresterhill, UK.
J Med Genet. 1995 Apr;32(4):282-3. doi: 10.1136/jmg.32.4.282.
Several antenatal cystic fibrosis carrier screening trials have offered women testing by either the stepwise or the couple method. In this study, both approaches were described to women attending an antenatal clinic, who were then asked which method they preferred. An estimate of the value to women of each type of test was also ascertained using a "willingness to pay" (WTP) method. Of 450 women, 279 (62%) preferred stepwise screening, 117 (26%) preferred couple screening, and 54 (12%) had no preference. Mean WTP for stepwise screening was 19 pounds (95% CI 17.50 pounds-20.50 pounds), and that for couple screening was 18 pounds (95% CI 16.50 pounds-19.50 pounds). The majority of women preferred stepwise screening although the average WTP for each method was similar.
多项产前囊性纤维化携带者筛查试验为女性提供了逐步筛查法或夫妇筛查法这两种检测方式。在本研究中，这两种方法均向就诊于产前诊所的女性进行了介绍，随后询问她们更喜欢哪种方法。还采用“支付意愿”（WTP）方法确定了每种检测方式对女性的价值估算。在450名女性中，279名（62%）更喜欢逐步筛查，117名（26%）更喜欢夫妇筛查，54名（12%）无偏好。逐步筛查的平均支付意愿为19英镑（95%置信区间为17.50英镑至20.50英镑），夫妇筛查的平均支付意愿为18英镑（95%置信区间为16.50英镑至19.50英镑）。尽管每种方法的平均支付意愿相似，但大多数女性更喜欢逐步筛查。
