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[Autologous blood stem cell transplantation-current status and issues. Fukuoka Bone Marrow Transplantation Group].

作者信息

Nagafuji K, Harada M

机构信息

First Department of Internal Medicine, Faculty of Medicine, Kyushu University.

出版信息

Rinsho Ketsueki. 1995 Jun;36(6):530-7.

PMID:7643446
Abstract

Autologous blood stem cell transplantation (ABSCT) has been increasingly used in the treatment of malignant diseases. With the use of hematopoietic cytokines, collection of peripheral blood stem cell (PBSC) has become easier. Contamination of PBSC with tumor cells is supposed to be reflecting the amount of residual tumor cells in the host. G-CSF combined conditioning regimen seems to be effective for ANLL in complete remission (CR) probably by in vivo purging of residual leukemic cells. From our preliminary results, ABSCT can be used as the treatment of choice for standard risk ANLL, and aggressive non-Hodgkin's lymphoma. To clarify the curative potential of ABSCT, prospective clinical trial consisting of remission induction, consolidation of CR, PBSC harvests, and marrow-ablative therapy for ABSCT will be required.

摘要

相似文献

1
[Autologous blood stem cell transplantation-current status and issues. Fukuoka Bone Marrow Transplantation Group].
Rinsho Ketsueki. 1995 Jun;36(6):530-7.
2
Cytokine-primed bone marrow stem cells vs. peripheral blood stem cells for autologous transplantation: a randomized comparison of GM-CSF vs. G-CSF.细胞因子预处理的骨髓干细胞与外周血干细胞用于自体移植：GM-CSF与G-CSF的随机对照比较
Biol Blood Marrow Transplant. 1997 Oct;3(4):217-23.
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Use of peripheral blood stem cells for autologous transplantation in acute myeloid leukemia patients allows faster engraftment and equivalent disease-free survival compared with bone marrow cells.与骨髓细胞相比，在急性髓系白血病患者中使用外周血干细胞进行自体移植可实现更快的植入和相当的无病生存期。
Bone Marrow Transplant. 1999 Sep;24(5):467-72. doi: 10.1038/sj.bmt.1701920.
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Successful second autologous blood stem cell transplantation after G-CSF-combined conditioning for the treatment of high-risk acute myelogenous leukemia.粒细胞集落刺激因子联合预处理后成功进行第二次自体造血干细胞移植治疗高危急性髓性白血病
Bone Marrow Transplant. 1994 Mar;13(3):325-7.
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[Clinical application of cytokines in peripheral blood stem cell transplantation].细胞因子在外周血干细胞移植中的临床应用
Rinsho Byori. 1993 Apr;41(4):384-9.
6
Autologous peripheral blood stem cell transplantation (PBSCT) mobilized with G-CSF in AML in first complete remission. Role of intensification therapy in outcome.在首次完全缓解的急性髓系白血病中，采用粒细胞集落刺激因子动员的自体外周血干细胞移植（PBSCT）。强化治疗对预后的作用。
Bone Marrow Transplant. 1998 Feb;21(4):375-82. doi: 10.1038/sj.bmt.1701102.
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Autologous transplantation of chemotherapy-purged PBSC collections from high-risk leukemia patients: a pilot study.高危白血病患者化疗清除后的外周血干细胞采集物的自体移植：一项试点研究。
Bone Marrow Transplant. 1999 Feb;23(3):235-41. doi: 10.1038/sj.bmt.1701576.
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Peripheral blood stem cell transplantation for relapsed or refractory aggressive lymphoma in patients over 60 years of age.60岁以上复发或难治性侵袭性淋巴瘤患者的外周血干细胞移植
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[Current possibilities in the treatment of high-malignity non-Hodgkin lymphoma, with special reference to autologous hematopoietic stem cell transplantation].[高恶性非霍奇金淋巴瘤的当前治疗可能性，特别提及自体造血干细胞移植]
Orv Hetil. 1994 Apr 17;135(16):843-7.
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Stem cell function and engraftment is not affected by "in vivo purging" with rituximab for autologous stem cell treatment for patients with low-grade non-Hodgkin's lymphoma.对于低度非霍奇金淋巴瘤患者，利妥昔单抗用于自体干细胞治疗时的“体内净化”不会影响干细胞功能及植入。
Semin Oncol. 1999 Oct;26(5 Suppl 14):115-22.

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Bone Marrow Transplant. 2015 Feb;50(2):301-3. doi: 10.1038/bmt.2014.236. Epub 2014 Oct 27.