大剂量静脉注射免疫球蛋白后发生的溶血性贫血。
Hemolytic anemia following high-dose intravenous immunoglobulin administration.
作者信息
Tamada K, Kohga M, Masuda H, Hattori K
机构信息
Division of Pediatrics, Tachikawa Kyosai Hospital (Federation of National Public Service and Affiliated Personnel Mutual Aid Associations), Tokyo, Japan.
出版信息
Acta Paediatr Jpn. 1995 Jun;37(3):391-3. doi: 10.1111/j.1442-200x.1995.tb03339.x.
We describe two cases of hemolytic anemia following high-dose intravenous human immunoglobulin administration in young females with idiopathic thrombocytopenic purpura. Inducement of hemolytic anemia by anti-A and anti-B antibodies in these cases necessitates the performance of a minor crossmatching procedure prior to immunoglobulin use to prevent the occurrence of this adverse reaction.
我们描述了两例患有特发性血小板减少性紫癜的年轻女性在大剂量静脉注射人免疫球蛋白后发生溶血性贫血的病例。在这些病例中，抗A和抗B抗体诱发溶血性贫血，因此在使用免疫球蛋白之前有必要进行次要交叉配血程序，以防止这种不良反应的发生。
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